Volume 14, Number 2—February 2008
Research
Genetic Determinants of Virulence in Pathogenic Lineage 2 West Nile Virus Strains
Elizabeth M. Botha*, Wanda Markotter*, Mariaan Wolfaardt*, Janusz T. Paweska†, Robert Swanepoel†, Gustavio Palacios‡, Louis H. Nel*, and Marietjie Venter*
Table 2
Percentage of amino acid and nucleotide differences when comparing the entire genome of selected West Nile virus strains*
| Strain | SA381/00 | H442 | SPU116/89 | SA93/01 | B956D117B3 | B956 | ANMg798 | NY-385–99 | NY-385–99 Clone TYP-9376 | NY-385–99 Clone 9317B | TM171–03 | MRM61C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SA381/00 | 2.4 | 3.6 | 3.7 | 3.1 | 2.9 | 15.8 | 20.6 | 20.6 | 20.6 | 20.6 | 20.5 | |
| H442 | 0.7 | 2.7 | 3.0 | 1.8 | 1.6 | 15.6 | 20.5 | 20.6 | 20.6 | 20.5 | 20.6 | |
| SPU116/89 | 0.9 | 0.7 | 1.3 | 2.0 | 1.9 | 16.0 | 20.8 | 20.9 | 20.9 | 20.8 | 20.7 | |
| SA93/01 | 0.8 | 0.7 | 0.6 | 2.3 | 2.2 | 15.7 | 20.8 | 20.9 | 20.9 | 20.8 | 20.6 | |
| B956D117B3 | 1.0 | 0.8 | 1.0 | 0.9 | 0.3 | 15.7 | 20.7 | 20.7 | 20.7 | 20.7 | 20.6 | |
| B956 | 0.7 | 0.6 | 0.7 | 0.7 | 0.7 | 15.8 | 20.7 | 20.7 | 20.7 | 20.7 | 20.6 | |
| AnMg798 | 3.4 | 3.3 | 3.5 | 3.4 | 3.5 | 3.4 | 21.5 | 21.5 | 21.5 | 21.4 | 21.2 | |
| NY-385–99 | 6.0 | 5.9 | 6.1 | 6.1 | 6.1 | 6 | 6.6 | 0.1 | 0.1 | 0.4 | 11.7 | |
| NY-385–99 Clone TYP-9376 | 6.1 | 6.0 | 6.2 | 6.2 | 6.2 | 6.1 | 6.7 | 0.1 | 0 | 0.5 | 11.8 | |
| NY-385–99 Clone 9317B | 6.1 | 6.0 | 6.2 | 6.2 | 6.2 | 6.1 | 6.7 | 0.1 | 0.0 | 0.5 | 11.8 | |
| TM171–03 | 6.0 | 5.9 | 6.1 | 6.1 | 6.1 | 6 | 6.7 | 0.1 | 0.2 | 0.2 | 11.8 | |
| MRM61C | 6.5 | 6.5 | 6.7 | 6.6 | 6.6 | 6.5 | 7.1 | 2.4 | 2.4 | 2.4 | 2.4 |
*The lower left matrix corresponds to amino acid sequences, and the upper right matrix corresponds to nucleotide sequences.
Page created: July 07, 2010
Page updated: July 07, 2010
Page reviewed: July 07, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.