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Volume 14, Number 4—April 2008

Research

Seroprevalence and Risk Factors for Human Herpesvirus 8 Infection, Rural Egypt1

Sam M. Mbulaiteye*Comments to Author , Ruth M. Pfeiffer*, Bryan Dolan*, Victor C.W. Tsang†, John Noh†, Nabiel N.H. Mikhail‡, Mohamed Abdel-Hamid§¶, Mohamed Hashem§¶, Denise Whitby#, G. Thomas Strickland¶, and James J. Goedert*
Author affiliations: *National Cancer Institute, Bethesda, Maryland, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ‡Assiut University, Cairo, Egypt; §National Hepatology and Tropical Medicine Research Institute, Cairo, Egypt; ¶University of Maryland School of Medicine, Baltimore, Maryland, USA; #National Cancer Institute-Frederick, Frederick, MD, USA;

Main Article

Table 2

Prevalence and crude OR of association of HHV-8 seropositivity with demographic, behavioral, and clinical characteristics among female patients, Egypt*

Characteristic
 n/N
 %
 OR
 95% CI
 p value†
Total 125/495 25.3 – – –
Age group, y <0.001
15–24 23/148 15.5 Ref – –
25–34 21/106 19.8 1.4 0.7–2.7 –
35–44 31/115 27.0 2.0 1.1–3.6 –
>45
 50/126
 39.7
 3.6
 2.1–6.3
 –
Education <0.001
None 88/307 28.7 Ref – –
Primary 34/154 32.7 0.7 0.4–1.1 –
Secondary/postsecondary
 4/38
 22.5
 0.3
 0.1–0.8
 –
Job 0.11
Other‡ 2/21 9.5 Ref – –
Housewife
 121/470
 25.7
 3.3
 0.8–14.3
 –
Dental treatments 0.02
No 49/239 20.5 Ref – –
Yes
 77/260
 29.6
 1.6
 1.1–2.5
 –
Tattoos 0.006
No 93/410 22.7 Ref – –
Present
 33/89
 37.1
 2.0
 1.2–3.3
 –
HCV serostatus 0.006
Negative 112/470 23.8 Ref – –
Positive
 14/29
 48.3
 3.0
 1.4–6.5
 –
Injections (lifetime) 0.03
<10 23/128 18.0 Ref – –
>10
 103/371
 27.8
 1.7
 1.1–2.9
 –
Schistosomiasis 0.94
Negative 48/189 25.4 Ref – –
Positive 76/303 25.1 1.0 0.6–1.5 –

*OR, odds ratio; HHV-8, human herpesvirus 8; CI, confidence interval; Ref, referrent; HCV, hepatitis C virus.
†p value for age group and education is test for trend; otherwise, p value is test for heterogeneity.
‡Job category for women: “Other” includes women who are students, are not working, or have technical or scientific jobs.

Main Article

1Results were presented, in part, at the 9th International Workshop on Kaposi’s Sarcoma–associated Herpesvirus (KSHV) and Related Agents, Cape Cod, Massachusetts, USA, July 12–15, 2006.

Page created: July 13, 2010
Page updated: July 13, 2010
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