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Volume 14, Number 7—July 2008


Determinants of Cluster Size in Large, Population-Based Molecular Epidemiology Study of Tuberculosis, Northern Malawi

Judith R. Glynn*Comments to Author , Amelia C. Crampin*†, Hamidou Traore*, Steve Chaguluka†, Donex T. Mwafulirwa†, Saad Alghamdi*, Bagrey M.M. Ngwira†, Malcolm D. Yates‡, Francis D. Drobniewski‡, and Paul E.M. Fine*
Author affiliations: *London School of Hygiene and Tropical Medicine, London, UK; †Karonga Prevention Study, Chilumba, Malawi; ‡Health Protection Agency, London;

Main Article

Table 2

Multivariate analysis of risk factors for larger cluster size, Malawi

Risk factor Cluster size*
p value
Odds ratio 95% CI
Age, y
<25 1 0.01†
25–34 1.0 0.66–1.5
35–44 0.76 0.48–1.2

Area <0.001
South, near Chilumba 0.54 0.33–0.90
Middle, near Nyungwe 1.3 0.81–2.0
Around Karonga 0.74 0.50–1.1
Karonga central (urban) 1
Kaporo area 0.48 0.30–0.76
Far north 0.55 0.32–0.92
Outside district 0.41 0.15–1.1

*Odds ratios are adjusted for the other factors shown in the table (i.e., the multivariate equation contained age group, sex, and area). CI, confidence interval.

Main Article