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Volume 14, Number 8—August 2008

CME ACTIVITY - Research

Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis

Manish M. Patel*Comments to Author , Marc-Alain Widdowson*, Roger I. Glass*†, Kenichiro Akazawa‡, Jan Vinjé*, and Umesh D. Parashar*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †National Institutes of Health, Bethesda, Maryland, USA; ‡Chigasaki Tokushukai Medical Center, Kanagawa, Japan;

Main Article

Table 3

Estimates of annual number of episodes of norovirus-associated diarrhea among children <5 years of age in industrialized and developing countries, by setting

SettingAnnual no. diarrhea-associated events*Pooled proportion of episodes attributable to noroviruses, %Total no. norovirus episodesAnnual incidence per 100,000 children†‡
Industrialized countries†
Outpatient7,743,00011.7906,0001,665
Inpatient531,00012.164,200118
Developing countries‡§
Inpatient9,015,00012.11,091,000197
Deaths1,800,00012.1218,00039

*Refer to Methods section of article.
†Industrialized countries’ incidence based on UNICEF 2003 population estimates of 54,425,000 children <5 y of age in developing countries (www.unicef.org/sowc05/english/Developingregional.html).
‡Developing countries’ incidence based on UNICEF 2003 population estimates of 552,742,000 children <5 y of age in industrialized (www.unicef.org/sowc05/english/Industrializedregional.html)
§Data from developing countries were sparse on fraction of norovirus-associated diarrhea episodes in the outpatient setting.

Main Article

Page created: July 12, 2010
Page updated: July 12, 2010
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