Volume 14, Number 8—August 2008
Dispatch
Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans
Donata Kalthoff*, Angele Breithaupt*, Jens P. Teifke*, Anja Globig*, Timm Harder*, Thomas C. Mettenleiter*, and Martin Beer*
Table 2
Viral shedding among mute swans with preexisting antibodies*
| Individual serologically positive | Viral excretion, no. days shedding replication competent virus (DPI) | Genome detection, no. days with positive PCR results (DPI) | Peak titer log10/mL swab (DPI) | Minimum Ct value (DPI) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| OS | CS | OS | CS | OS | CS | OS | CS | ||||
| No. 1 (contact) | 1 (3) | 0 | 7 (3-9) | 6 (3-8) | 1.75 (3) | 0 | 32.12 (4) | 31.65 (4) | |||
| No. 7 | 4 (2–5) | 1 (4) | 8 (1–8) | 6 (3–7, 9) | 2.63 (4) | 1.75 (4) | 26.44 (5) | 29.49 (4) | |||
*H5-specific real-time reverse transcription–PCR (RT-PCR) results of swab samples from swans. DPI, days postinoculation; Ct value, cycle threshold of the real-time RT-PCR; OS, oropharyngeal swab; CS, cloacal swab.
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