Volume 15, Number 1—January 2009
Letter
Vertical Transmission of Pneumocystis jirovecii in Humans
Marco A. Montes-Cano
, Magali Chabe, Maria Fontillon-Alberdi, Carmen de la Horra, Nieves Respaldiza, Francisco J. Medrano, Jose M. Varela, Eduardo Dei-Cas, and Enrique J. Calderon
, Magali Chabe, Maria Fontillon-Alberdi, Carmen de la Horra, Nieves Respaldiza, Francisco J. Medrano, Jose M. Varela, Eduardo Dei-Cas, and Enrique J. Calderon
Table
Pneumocystis jirovecii genotypes in samples identified as positive by nested PCR for 2 loci from fetal lung tissues and placenta samples*
| Case | Lung tissues |
Placenta tissues |
|||
|---|---|---|---|---|---|
| mtLSU-rRNA genotype | DHPS genotype | mtLSU-rRNA genotype | DHPS genotype | ||
| C1 | 3 | 1 | – | – | |
| C2 | 1 | 1 | 1 | – | |
| C3 | 3 | 1 | – | – | |
| C4 | 3 | 1 | – | – | |
| C5 | 2 | 1 | 1 | – | |
| C6 | 1 | 1 | 3 | – | |
| C7 | 1 | 1 | – | – | |
| C8 | – | – | 1 | 1 | |
| C9 | 3 | – | – | – | |
| C10 | – | – | 3 | – | |
| C11 | 3 | – | 1 and 3 | – | |
| C12 | 1 and 3 | – | 1 | – | |
| C13 | – | – | 1 | – | |
| C14 | 3 | – | – | – | |
| C15-C20 | – | – | – | – | |
*Genotype 1, polymorphism 85C/248C in mitochondrial large subunit (mtLSU)–rRNA gene and 55 Trh/57 Pro indihydropteroate synthase (DHPS) gene; genotype 2, polymorphism in 85A/248C; genotype 3, polymorphism in 85T/248C.
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