Volume 15, Number 12—December 2009
Research
Genomic Signatures of Influenza A Pandemic (H1N1) 2009 Virus
Guang-Wu Chen
and Shin-Ru Shih
and Shin-Ru Shih
Table 2
Amino acid residues of pandemic (H1N1) 2009 virus strains at 8 positions where swine–human signatures are located*
| Gene | Position | Swine virus residue (all subtypes) | Human virus residue | Pandemic (H1N1) 2009 virus residue |
|---|---|---|---|---|
| PB2 |
44 |
A(301), S(27), C(1) |
S(2,734), A(30), L(2) |
A(61) |
| PA | 268 | L(325), I(31), T(1) | I(2,724), L(35), V(2) | L(61) |
| 552 |
T(280), S(25) |
S(2,721), T(10), N(2), I(1), R(1) |
T(61) |
|
| M1 |
137 |
T(429), A(39) |
A(3,577), T(25) |
T(146) |
| M2 | 57 | Y(343), H(23), R(2) | H(3,804),Y(65), D(25), Q(5), R(5), N(4) | Y(55) |
| 86 | V(324), A(24), S(1) | A(3,781), V(26), T(10), D(1) | V(55) | |
| 93 |
N(320), S(23) |
S(3,699), N(69), Q(2), R(1), H(1), I(1) |
N(55) |
|
| NS2 | 107 | L(299), F(25) | F(2,850), L(45), S(1), V(1) | L(93) |
*Boldface indicates dominant amino acid residue type. PB, polymerase B; PA, polymerase A; M, matrix; NS, nonstructural.
Page created: December 09, 2010
Page updated: December 09, 2010
Page reviewed: December 09, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
Content Credential