Volume 15, Number 2—February 2009
Dispatch
Genomic Characterization of Novel Human Parechovirus Type
Linlin Li, Joseph Victoria, Amit Kapoor, Asif Naeem, Shahzad Shaukat, Salmaan Sharif, Muhammad Masroor Alam, Mehar Angez, Sohail Zahoor Zaidi, and Eric Delwart
Table 1
Nucleotide and amino acid sequence comparisons of HPeV7 candidate prototype PAK5045 with the HPeV prototypes*
| Sequence | % Nucleotide (amino acid) identity |
|||||
|---|---|---|---|---|---|---|
| HPeV1 | HPeV2 | HPeV3 | HPeV4 | HPeV5 | HPeV6 | |
| 5′ UTR | 87.6 | 86.8 | 95.9 | 90.2 | 86.7 | 89.8 |
| VP0 | 71.0 (76.8) | 69.6 (75.8) | 68.3 (72.3) | 69.7 (75.1) | 70.1 (75.4) | 69.7 (73.7) |
| VP3 | 69.5 (75.3) | 69.9 (74.1) | 73.2 (83.9) | 70.3 (77.5) | 69.7 (74.0) | 68.8 (74.0) |
| VP1 | 65.8 (69.9) | 66.6 (69.5) | 68.9 (77.0) | 67.8 (68.6) | 64.7 (66.4) | 63.9 (65.0) |
| 2A | 77.9 (89.3) | 75.2 (84.6) | 77.5 (85.9) | 80.8 (89.3) | 80.5 (89.9) | 76.5 (85.9) |
| 2B | 80.1 (95.9) | 76.8 (95.1) | 86.1 (99.2) | 83.6 (99.2) | 83.6 (97.5) | 78.7 (96.7) |
| 2C | 78.9 (91.5) | 76.5 (86.6) | 83.8 (96.0) | 85.9 (97.0) | 80.9 (94.5) | 79.5 (90.0) |
| 3A | 76.6 (88.0) | 76.1 (83.8) | 81.8 (94.0) | 87.5 (96.6) | 78.9 (82.9) | 76.1 (89.7) |
| 3B | 73.3 (90.0) | 75.0 (90.0) | 76.7 (85.0) | 85.0 (95.0) | 76.7 (90.0) | 70.0 (90.0) |
| 3C | 81.3 (98.0) | 81.2 (98.0) | 83.5 (98.0) | 86.3 (98.0) | 80.3 (99.0) | 83.0 (99.0) |
| 3D | 83.2 (94.9) | 82.8 (94.0) | 88.7 (96.8) | 90.8 (97.2) | 83.8 (95.9) | 83.6 (95.3) |
| 3′ UTR | 85.1 | 89.8 | 95.5 | 94.4 | 85.2 | 83.0 |
| ORF | 76.3 (86.7) | 75.6 (84.8) | 79.5 (89.1) | 80.8 (88.5) | 77.0 (86.6) | 76.0 (85.4) |
*Sequences for the HPeV prototypes, HPeV1 (Harris, S45208), HPeV2 (Williamson, AJ005695), HPeV3 (A308/99, AB084913), HPeV4 (K251176-02, DQ315670), HPeV5 (CT86-6760, AF055846), and HPeV6 (NII561–2000, AB252582), were obtained from GenBank. HPeV, human parechoviruses.
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