Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 15, Number 2—February 2009
Dispatch

Novel Human Parechovirus from Brazil

Ana Maria Bispo de Filippis, Klaus Grywna, Andreas Stöcker, Patrícia Silva Almeida, Tereza Cristina Medrado Ribeiro, Monika Eschbach-Bludau, Nadine Petersen, Hugo da Costa Ribeiro, and Sung Sup ParkComments to Author 
Author affiliations: University Hospital Prof Edgard Santos, Federal University of Bahia, Salvador, Brazil (J.F. Drexler, A. Stöcker); Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany (J.F. Drexler, N. Petersen); University of Bonn Medical Centre, Bonn, Germany (J.F. Drexler, K. Grywna, M. Eschbach-Bludau, C. Drosten); Federal University of Bahia, Salvador (P. Silva Almeida, T.C. Medrado Ribeiro, H. da Costa Ribeiro, Jr.)

Main Article

Figure 1

Evolutionary relationships between known parechoviruses and the new human parechovirus from this study (boldface). Phylogenetic analyses of A) complete viral protein (VP) 1, B) VP0, and C) VP3, and D) the whole nonstructural region (comprising regions P2 and P3), were constructed using the Jones-Taylor-Thornton matrix-based substitution model on an amino acid–driven alignment (pairwise deletion option). The evolutionary histories were inferred using the neighbor-joining method and are in the uni

Figure 1. Evolutionary relationships between known parechoviruses and the new human parechovirus from this study (boldface). Phylogenetic analyses of A) complete viral protein (VP) 1, B) VP0, and C) VP3, and D) the whole nonstructural region (comprising regions P2 and P3), were constructed using the Jones-Taylor-Thornton matrix-based substitution model on an amino acid–driven alignment (pairwise deletion option). The evolutionary histories were inferred using the neighbor-joining method and are in the units of the number of amino acid substitutions per site. Relevant bootstrap values from 500 replicate trees are shown next to the branches. The scale bars show the evolutionary distance from each root. Analysis was conducted in MEGA software version 4 (www.megasoftware.net). HPeV reference strains are named in full detail; their GenBank accession numbers are not further indicated. Contemporary HPeV1 strain BNI-788st accession number was EF051629 and HPeV6 strain BNI-67 accession number was EU022171. The tree was rooted against Ljungan virus, a rodent parechovirus (GenBank accession no. EF202833). In the P2/P3 tree, branches to the Ljungan virus node have been truncated for space reasons, as indicated by dotted lines.

Main Article

Page created: December 08, 2010
Page updated: December 08, 2010
Page reviewed: December 08, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external