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Volume 15, Number 6—June 2009

Japanese Encephalitis Viruses from Bats in Yunnan, China

Jing-Lin Wang1, Xiao-Ling Pan1, Hai-Lin Zhang, Shi-Hong Fu, Huan-Yu Wang, Qing Tang, Lin-Fa Wang, and Guo-Dong LiangComments to Author 

Author affiliations: Institute for Viral Disease Control and Prevention, Beijing, People’s Republic of China (J.-L. Wang, X.-L. Pan, S.-H. Fu, H-Y. Wang, Q. Tang, G.-D. Liang); Yunnan Institute of Endemic Disease Control and Prevention, Dali City, People’s Republic of China (J.-L. Wang, H.-L. Zhang); Australian Commonwealth Scientific and Industrial Research Organisation Australian Animal Health Laboratory, Geelong, Victoria, Australia (L.-F. Wang)

Main Article

Table 2

Comparison of key amino acid residues of the E protein of Japanese encephalitis virus important for neurovirulence*

Strain E107 E138 E176 E177 E264 E279 E315 E439
SA14-14-2 Phe Lys Val Ala His Met Val Arg
B58 Leu Glu Ile Thr Gln Lys Ile Lys
GB30 Leu Glu Ile Thr Gln Lys Ile Lys
Nakayama Leu Glu Ile Thr Gln Lys Ile Lys

*These 8 aa residues of the envelope protein are shown to play a key role in neurovirulence. They vary substantially between the attenuated vaccine strain (SA14-14-2) and the virulent strain (Nakayama).

Main Article

1These authors contributed equally to this article.

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