Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Volume 16, Number 4—April 2010

Research

Influenza A Strain-Dependent Pathogenesis in Fatal H1N1 and H5N1 Subtype Infections of Mice

Mutien-Marie Garigliany, Adélite Habyarimana, Bénédicte Lambrecht, Els Van de Paar, Anne Cornet, Thierry van den Berg, and Daniel DesmechtComments to Author 
Author affiliations: University of Liège, Liège, Belgium (M.-M. Garigliany, E. Van de Paar, A. Cornet, D. Desmecht); Veterinary Agrochemical Center, Brussels, Belgium (A. Habyarimana, B. Lambrecht, T. van den Berg).

Main Article

Figure 7

Topologic distribution of antigens in mice infected with influenza A virus subtype H1N1 at day 7 postinfection (left columns) and subtype H5N1 at day 4 postinfection (right columns) in various nonrespiratory organs. A) Glial cells (mostly oligodendrocytes); B) cardiomyocytes; C) spleen macrophages; D) hepatocytes; E) islets of Langerhans cells in the pancreas; and F) adipocytes. Bright virus-positive staining can be seen in subtype H5N1–infected mice (antinucleoprotein immunohistochemical staini

Figure 7. Topologic distribution of antigens in mice infected with influenza A virus subtype H1N1 at day 7 postinfection (left columns) and subtype H5N1 at day 4 postinfection (right columns) in various nonrespiratory organs. A) Glial cells (mostly oligodendrocytes); B) cardiomyocytes; C) spleen macrophages; D) hepatocytes; E) islets of Langerhans cells in the pancreas; and F) adipocytes. Bright virus-positive staining can be seen in subtype H5N1–infected mice (antinucleoprotein immunohistochemical staining), while absence of any staining can be seen in subtype H1N1–infected mice (Mayer hematoxylin counterstain). Original magnification ×100.

Main Article

Page created: December 28, 2010
Page updated: December 28, 2010
Page reviewed: December 28, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external