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Volume 16, Number 8—August 2010

Novel Mycobacterium tuberculosis Complex Pathogen, M. mungi

Kathleen A. AlexanderComments to Author , Pete N. Laver, Anita L. Michel, Mark Williams, Paul D. van Helden, Robin M. Warren, and Nicolaas C. Gey van Pittius
Author affiliations: Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA (K.A. Alexander, P.N. Laver); Centre for Conservation of African Resources; Animals, Communities and Land Use, Kasane, Botswana (K.A. Alexander, P.N. Laver); ARC-Onderstepoort Veterinary Institute, Pretoria, South Africa (A.L. Michel); University of Pretoria, Pretoria (A.L. Michel, M. Williams); Stellenbosch University, Tygerberg, South Africa (P.D. van Helden, R.M. Warren, N.C. Gey van Pittius)

Main Article

Table 1

Genomic regions of difference of Mycobacterium tuberculosis complex members compared with M. mungi*

Mycobacterium species Region of difference
RD1BCG RD4 RD9 RD12 RD1mic RD2seal
M. canettii P P P A P P
M. tuberculosis P P P P P P
M. africanum P P A P P A
M. microti P P A P A P
M. pinnipedii P P A P P A
M. caprae P P A A P P
M. bovis P A A A P P
M. bovis BCG A A A A P P
M. mungi P P A P P P

*Determined by PCR amplification (5). RD, region of difference; RD1BCG, M. bovis BCG–specific RD1; RD1mic, M. microti–specific RD1; RD2seal, M. pinnipedii–specific RD2; P, present; A, absent.

Main Article

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