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Volume 16, Number 9—September 2010
Research

Long-Term Health Risks for Children and Young Adults after Infective Gastroenteritis

Rachael E. MoorinComments to Author , Jane S. Heyworth, Geoffrey M. Forbes, and Thomas V. Riley
Author affiliations: Author affiliations: The University of Western Australia, Crawley, Western Australia, Australia (R.E. Moorin, J.S. Heyworth, T.V. Riley); Royal Perth Hospital, Perth, Western Australia, Australia (G.M. Forbes)

Main Article

Table A2

Significance, hazard ratios, and 95% CIs of variables in the 3 models measuring sequelae in children and young adults after infective gastroenteritis*

p value HR (95% CI) p value HR (95% CI)
Previous history of an enteric infection Yes <0.0001 1.642 (1.590–1.695) <0.0001 1.628 (1.574–1.684)
Sex Female <0.0001 0.806 (0.790–0.822) <0.0001 0.789 (0.772–0.806)
Indigenous status Aboriginal <0.0001 1.807 (1.728–1.890) <0.0001 1.897 (1.810–1.988)
Singleton birth Yes 0.0071 1.090 (1.024–1.160) 0.0084 1.094 (1.023–1.170)
Year of birth <0.0001 0.978 (0.976–0.981) <0.0001 0.989 (0.986–0.991)
Age in years at enteric infection or proxy
<0.0001
 0.872 (0.868–0.877)
<0.0001
 0.810 (0.805–0.815)
Weight at birth, g <2,000 <0.0001 1.000 <0.0001 1.000
2,001–3,000 <0.0001 0.799 (0.747–0.854 <0.0001 0.768 (0.715–0.824)
3,001–4,000 <0.0001 0.745 (0.698–0.796) <0.0001 0.706 (0.658–0.756)
4,001–5,000 <0.0001 0.728 (0.678–0.782) <0.0001 0.686 (0.636–0.740)
>5,001
 0.0747
 0.809 (0.641–1.021)
0.0871
 0.808 (0.633–1.032)
Socioeconomic status (SEIFA) Extremely advantaged <0.0001 1.000 <0.0001 1.000
Advantaged 0.1977 1.022 (0.989–1.057) 0.1657 1.026 (0.989–1.064)
Average 0.0003 1.066 (1.029–1.103) 0.0005 1.069 (1.029–1.111)
Disadvantaged <0.0001 1.143 (1.110–1.177) <0.0001 1.166 (1.129–1.204)
Extremely disadvantaged
 <0.0001
 1.112 (1.079–1.146)
<0.0001
 1.122 (1.086–1.159)
Accessibility to services Highly accessible <0.0001 1.000 <0.0001 1.000
Accessible <0.0001 1.183 (1.141–1.227) <0.0001 1.203 (1.157–1.252)
Moderately accessible <0.0001 1.218 (1.175–1.262) <0.0001 1.257 (1.210–1.306)
Remote <0.0001 1.329 (1.260–1.402) <0.0001 1.410 (1.333–1.492)
Very remote
 <0.0001
 1.149 (1.102–1.197)
<0.0001
 1.206 (1.154–1.260)
Born in hospital
 Yes
 <0.0001
 0.883 (0.838–0.931)
<0.0001
 0.820 (0.776–0.867)
Mother’s region of birth Australia <0.0001 1.000 <0.0001 1.000
New Zealand 0.0006 0.852 (0.778–0.934) 0.0108 0.880 (0.798–0.971)
United Kingdom 0.0018 0.925 (0.881–0.972) 0.0131 0.935 (0.886–0.986)
North America 0.1076 0.833 (0.668–1.041) 0.1996 0.853 (0.668–1.088)
Europe 0.0101 0.886 (0.808–0.972) 0.0106 0.874 (0.788–0.969)
Eastern Europe, former USSR, and Baltic States 0.3687 0.897 (0.709–1.136) 0.5647 0.926 (0.711–1.204)
Africa 0.1407 0.912 (0.808–1.031) 0.2897 0.931 (0.816–1.063)
Central/South America and Caribbean 0.7729 0.964 (0.754–1.233) 0.4821 0.906 (0.687–1.194)
Melanesia, Micronesia, and Polynesia 0.2428 0.804 (0.558–1.159) 0.2646 0.796 (0.534–1.188)
Asia <0.0001 0.593 (0.545–0.645) 0.0000 0.600 (0.546–0.659)
Middle East
 0.3621
 0.892 (0.699–1.140)
0.2494
 0.855 (0.655–1.116)
Father’s region of birth Australia <0.0001 1.000 <0.0001 1.000
New Zealand 0.0989 0.950 (0.893–1.010) 0.2285 0.960 (0.899–1.026)
United Kingdom 0.0580 1.033 (0.999–1.069) 0.1773 1.026 (0.989–1.065)
North America 0.1267 0.910 (0.806–1.027) 0.1727 0.912 (0.799–1.041)
Europe (N,S, and W) 0.0239 0.934 (0.881–0.991) 0.0083 0.915 (0.857–0.977)
Eastern Europe, former USSR, and Baltic States 0.1320 0.853 (0.693–1.049) 0.0285 0.768 (0.606–0.973)
Africa 0.0894 0.924 (0.843–1.012) 0.1606 0.931 (0.843–1.029)
Central/South America and Caribbean 0.8662 1.019 (0.822–1.261) 0.8923 1.016 (0.803–1.286)
Melanesia, Micronesia, and Polynesia 0.3944 0.906 (0.721–1.138) 0.5997 0.937 (0.733–1.196)
Asia <0.0001 0.847 (0.785–0.914) <0.0001 0.825 (0.758–0.897)
Middle East
 0.1435
 0.857 (0.697–1.054)
0.3362
 0.897 (0.718–1.120)
Hospitalization for a concurrent illness Yes <0.0001 0.814 (0.766–0.864) <0.0001 6.671 (5.637–7.893)

*HR, hazard ratio; CI, confidence interval; USSR, Union of Soviet Socialist Republics; –, not applicable.

Main Article

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