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Volume 17, Number 1—January 2011
Dispatch
Seasonal Influenza A (H1N1) Infection in Early Pregnancy and Second Trimester Fetal Demise
Richard W. Lieberman
, Natasha Bagdasarian, Dafydd Thomas, and Cosmas Van De Ven
, Natasha Bagdasarian, Dafydd Thomas, and Cosmas Van De Ven
Figure 1
Figure 1. Tissue sample from 30-year-old primigravida patient exposed to seasonal influenza (H1N1). A) Intervillous (maternal) spaces with clusters/sheets of histiocytes (chronic intervillositis) and fibrotic fetal chorionic villi with Hofbauer cells–histiocytic inflammation (hematoxylin and eosin stain, original magnification ×200). B) Dual-stained immunofluorescent assay showing antibodies to influenza A virus (H1N1) (tetramethylrhodamine isothiocyanate, red) and cytokeratin (fluorescein isothiocyanate, green) in intravillous (fetal) and intervillous (maternal) space.
- Page created: June 30, 2011
- Page last updated: June 30, 2011
- Page last reviewed: June 30, 2011
- Centers for Disease Control and Prevention,
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National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)
Office of the Director (OD)