Volume 17, Number 10—October 2011
Research
Oseltamivir-Resistant Pandemic (H1N1) 2009 Virus Infection in England and Scotland, 2009–2010
Laurence Calatayud
, Angie Lackenby, Arlene Reynolds, Jim McMenamin, Nick F. Phin, Maria Zambon, and Richard G. Pebody
, Angie Lackenby, Arlene Reynolds, Jim McMenamin, Nick F. Phin, Maria Zambon, and Richard G. Pebody
Table 4
Distribution and reported associations of outcomes (complications, ICU admission, death) for study patients and controls hospitalized for pandemic (H1N1) 2009, England and Scotland, April 27, 2009–April, 30, 2010*
| Outcome | Case-patients with oseltamivir-resistant strains, n = 34 | Controls with oseltamivir-sensitive strains, n = 346 | OR (95% CI) | |||||
|---|---|---|---|---|---|---|---|---|
| n | No. (%) with outcome | n | No. (%) with outcome | Crude | Adjusted† | |||
| Any complications | 25 | 21 (84.0) | 346 | 76 (22.0) | 18.6 (6.0–76.2) | 9.0 (2.4–34.3) | ||
| Respiratory complications | 24 | 19 (79.2) | 346 | 67 (19.4) | 15.8 (5.4–55.6) | 6.6 (1.8–23.3) | ||
| ICU admission | 23 | 12 (52.01) | 205 | 59 (28.8) | 2.3 (1.0–7.1) | 2.3 (0.7–7.9) | ||
| Death | 30 | 11 (36.7) | 322 | 18 (5.6) | 9.8 (3.6–25.4) | 2.2 (0.5–9.5)
*n indicates no. patients with information available for that category. ICU, intensive care unit, OR, odds ratio; CI, confidence interval. | ||
*n indicates no. patients with information available for that category. ICU, intensive care unit, OR, odds ratio; CI, confidence interval.
†OR adjusted for age, sex, and underlying conditions (e.g., immunosuppression, chronic respiratory diseases).
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