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Volume 17, Number 12—December 2011
Research

Hepatitis E Virus in Rats, Los Angeles, California, USA

Robert H. Purcell, Ronald E. Engle, Michael P. Rood, Yamina Kabrane-Lazizi1, Hanh T. Nguyen, Sugantha Govindarajan, Marisa St. Claire2, and Suzanne U. EmersonComments to Author 
Author affiliations: National Institutes of Health, Bethesda Maryland, USA (R.H. Purcell, R.E. Engle, Y. Kabrane-Lazizi, H.T. Nguyen, S.U. Emerson); Department of Public Health Services, Los Angeles, California, USA (M.P. Rood); Rancho Los Amigos Hospital, Downey, California, USA (S. Govindarajan); Bioqual, Inc., Rockville, Maryland, USA (M. St. Claire)

Main Article

Table 2

Rat HEV in serial fecal samples of experimentally infected laboratory rats, Los Angeles, California. USA*

Animal Day postinfection
7 9 11 13 15 17 19 21 23 25 27 29 31 33 35
Rat B76
Infectious† NT NT NT – + – + – – – – – – NT NT
RT-PCR NT NT NT + + + + + + – – – – NT NT
Serum antibody against HEV NT NT NT – – – – – – – – + + + +
Rat B84
Infectious† + – + + + – – – – – NT NT NT NT NT
RT-PCR + + + + + – – – – – NT NT NT NT NT
Serum antibody against HEV – – – – – – – + + + + + + + +

*HEV, hepatitis E virus; NT, not tested; –, negative; +, positive; RT-PCR, reverse transcription PCR.
†As measured by transmission to another rat.

Main Article

1Current affiliation: Embassy of France, Beijing, People’s Republic of China.

2Current affiliation: National Institutes of Health, Frederick, Maryland, USA.

Page created: November 30, 2011
Page updated: November 30, 2011
Page reviewed: November 30, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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