Volume 17, Number 6—June 2011
Dispatch
Immunologic Changes during Pandemic (H1N1) 2009, China
Hong-Hui Shen1, Jun Hou1, Wei-Wei Chen, Bing-Ke Bai, Hai-Bin Wang, Tong-Sheng Guo, Ai-Xia Liu, Yong-Li Li, Min Zhao, Pan-Yong Mao, Jin Li, Bo-An Li
, and Yuan-Li Mao1
, and Yuan-Li Mao1
Table
Flow cytometric analysis of peripheral blood lymphocyte subsets for 28 patients with pandemic (H1N1) 2009 at hospitalization, China*
| Lymphocyte subset | No. positive/no. tested (%) |
|---|---|
| CD45 <1,500 cells/mm3† |
21/28 (75.0) |
| CD3 | |
| <690 cells/mm3 | 9/28 (32.1) |
| <55% |
4/28 (14.3) |
| CD4 | |
| <400 cells/mm3 | 13/28 (46.4) |
| <31% |
8/28 (28.6) |
| CD8 | |
| <190 cells/mm3 | 3/28 (10.7) |
| <13% |
0/28 (0) |
| B cells | |
| <90 cells/mm3 | 1/28 (3.6) |
| <6% |
0/28 (0) |
| Natural killer cells | |
| >590 cells/mm3 | 1/28 (3.6) |
| >27% |
4/28 (14.3) |
| Ratio of CD4:CD8 cells <1.4 | 14/28 (50.0) |
*Lymphocyte subsets were defined as the following combinations: CD3+/CD45+ for CD3 T-lymphocytes; CD3+/CD4/+/CD45+ for CD4 T-lymphocytes; CD3+/CD8+/CD45+ for CD8 T-lymphocytes; CD19+/CD45+ for B-lymphocytes; and CD3+/CD(16+56)+/CD45+ for natural killer cells.
†CD45 lymphocyte count was designated the total lymphocyte count.
1These authors contributed equally to this article.
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