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Volume 17, Number 6—June 2011
Dispatch

Increasing Ceftriaxone Resistance in Salmonellae, Taiwan

Lin-Hui Su, Wen-Shin Teng, Chyi-Liang Chen, Hao-Yuan Lee, Hsin-Chieh Li, Tsu-Lan Wu, and Cheng-Hsun ChiuComments to Author 
Author affiliations: Author affiliations: Chang Gung Memorial Hospital, Taoyuan, Taiwan (L.-H. Su, H.-C. Li, T.-L. Wu); Chang Gung University College of Medicine, Taoyuan (L.-H. Su, W.-S. Teng, H.-Y. Lee, T.-L. Wu, C.-H. Chiu); Chang Gung Children’s Hospital, Taoyuan (W.-S. Teng, C.-L. Chen, H.-Y. Lee, C.-H. Chiu)

Main Article

Table 2

Characteristics of conjugative blaCMY-2-harboring IncI1 plasmids derived in this study and comparison of pMLST patterns with similar plasmids published previously*

IncI1 plasmid
 Salmonella enterica serotype or Escherichia coli
 Susceptibility profile†
 Country
 Year of isolation
 pMLST‡ ST§
 Clonal complex
 Reference
repI1
 ardA
 trbA
 sogS
 pilL
pSC-B134 Choleraesuis R/S/S Taiwan 2007 1 1 15 9 3 51 NA This study
pSC-B136 Choleraesuis R/R/S Taiwan 2008 1 4 15 11 2 52 NA This study
pSB-5 Typhimurium
variant Copenhagen R/R/R Taiwan 2010 2 1 15 11 2 53 NA This study
pSB28 Typhimurium S/S/S Taiwan 2010 1 4 5 11 2 54 NA This study
pSB151 Typhimurium S/S/S Taiwan 2010 4 5 15 11 3 55 NA This study
pSB193 Typhimurium S/S/S Taiwan 2010 1 4 5 11 2 54 NA This study
pSB105 Agona R/S/S Taiwan 2010 2 1 15 11 3 56 NA This study
pSD166 Enteritidis R/S/S Taiwan 2010 2 1 15 11 3 56 NA This study
398T E. coli NA Italy 2006 1 2 3 2 1 2 CC-2 (12)
05–1909 Heidelberg NA Canada 2005 1 2 3 2 1 2 CC-2 (13)
1358T Thompson NA USA 1996 1 3 3 4 1 4 CC-12 (12)
DH-20406 Heidelberg NA USA 2004 1 4 3 4 1 12 CC-12 (14)
06–3048 4,5,12:i:– NA Canada 2006 1 4 3 4 1 12 CC-12 (13)
06–3539 Agona NA Canada 2006 1 4 3 4 1 12 CC-12 (13)
N07–0084 E. coli NA Canada 2005 1 4 3 4 1 12 CC-12 (13)
05–2835 Heidelberg NA Canada 2005 1 4 3 4 1 12 CC-12 (13)
06–3985 Litchfield NA Canada 2006 1 4 3 4 1 12 CC-12 (13)
05–5567 Typhimurium NA Canada 2005 1 4 3 4 1 12 CC-12 (13)
N06–523 E. coli NA Canada 2006 1 4 3 2 1 18 CC-2/ CC-12 (13)
N06–0537 E. coli NA Canada 2006 1 3 3 4 3 19 CC-12 (13)
05–6117 4,5,12:1:– NA Canada 2006 1 1 3 9 1 20 NA (13)
N07–0093 E. coli NA Canada 2005 1 1 3 9 1 20 NA (13)
06–0753 Heidelberg NA Canada 2006 1 2 11 3 3 21 CC-5 (13)
N07–0079 E. coli NA Canada 2005 1 6 3 4 1 22 CC-12 (13)
N07–0081 E. coli NA Canada 2005 1 2 3 1 1 23 CC-2 (13)

*pMLST, plasmid multilocus sequence typing; ST, sequence type; R, resistant; S, susceptible; NA, not applicable.
†Antimicrobial drug susceptibility to chloramphenicol, trimethoprim/sulfamethoxazole, and quinolones (nalidixic acid and ciprofloxacin). The transconjugants were also resistant to ampicillin and ceftriaxone.
‡pMLST results were compared to those published in the plasmid MLST website (http://pubmlst.org/plasmid).
§STs were designated according to the different combinations of allele variants observed among the IncI1 plasmids.

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References
  1. Vugia  DJ, Samuel  M, Farley  MM, Marcus  R, Shiferaw  B, Shallow  S, Invasive Salmonella infections in the United States, FoodNet, 1996–1999: incidence, serotype distribution, and outcome. Clin Infect Dis. 2004;38(Suppl 3):S149–56. DOIPubMedGoogle Scholar
  2. Su  LH, Chiu  CH, Chu  C, Ou  JT. Antimicrobial resistance in nontyphoid Salmonella serotypes: a global challenge. Clin Infect Dis. 2004;39:546–51. DOIPubMedGoogle Scholar
  3. Chiu  CH, Wu  TL, Su  LH, Chu  C, Chia  JH, Kuo  AJ, The emergence in Taiwan of fluoroquinolone resistance in Salmonella enterica serotype choleraesuis. N Engl J Med. 2002;346:413–9. DOIPubMedGoogle Scholar
  4. Chiu  CH, Su  LH, Chu  C, Chia  JH, Wu  TL, Lin  TY, Isolation of Salmonella enterica serotype choleraesuis resistant to ceftriaxone and ciprofloxacin. Lancet. 2004;363:1285–6. DOIPubMedGoogle Scholar
  5. Ye  J, Su  LH, Chen  CL, Hu  S, Wang  J, Yu  J, Complete nucleotide sequence of pSC138, the multidrug resistance plasmid of Salmonella enterica serotype Choleraesuis SC-B67. Plasmid. 2011;65:132–40. DOIPubMedGoogle Scholar
  6. Su  LH, Chen  HL, Chia  JH, Liu  SY, Chu  C, Wu  TL, Distribution of a transposon-like element carrying blaCMY-2 among Salmonella and other Enterobacteriaceae. J Antimicrob Chemother. 2006;57:424–9. DOIPubMedGoogle Scholar
  7. Su  LH, Leu  HS, Chiu  YP, Chia  JH, Kuo  AJ, Sun  CF, Molecular investigation of two clusters of nosocomial bacteraemia caused by multiresistant Klebsiella pneumoniae using pulsed-field gel electrophoresis and infrequent-restriction-site PCR. J Hosp Infect. 2000;46:110–7. DOIPubMedGoogle Scholar
  8. Kado  CI, Liu  ST. Rapid procedure for detection and isolation of large and small plasmids. J Bacteriol. 1981;145:1365–73.PubMedGoogle Scholar
  9. Southern  EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975;98:503–17. DOIPubMedGoogle Scholar
  10. Carattoli  A, Bertini  A, Villa  L, Falbo  V, Hopkins  KL, Threlfall  EJ. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods. 2005;63:219–28. DOIPubMedGoogle Scholar
  11. Jacoby  GA, Han  P. Detection of extended-spectrum β-lactamases in clinical isolates of Klebsiella pneumoniae and Escherichia coli. J Clin Microbiol. 1996;34:908–11.PubMedGoogle Scholar
  12. García-Fernández  A, Chiaretto  G, Bertini  A, Villa  L, Fortini  D, Ricci  A, Multilocus sequence typing of IncI1 plasmids carrying extended-spectrum β-lactamases in Escherichia coli and Salmonella of human and animal origin. J Antimicrob Chemother. 2008;61:1229–33. DOIPubMedGoogle Scholar
  13. Mataseje  LF, Baudry  PJ, Zhanel  GG, Morck  DW, Read  RR, Louie  M, Comparison of CMY-2 plasmids isolated from human, animal, and environmental Escherichia coli and Salmonella spp. from Canada. Diagn Microbiol Infect Dis. 2010;67:387–91. DOIPubMedGoogle Scholar
  14. Folster  JP, Pecic  G, Bolcen  S, Theobald  L, Hise  K, Carattoli  A, Characterization of extended-spectrum cephalosporin-resistant Salmonella enterica serovar Heidelberg isolated from humans in the United States. Foodborne Pathog Dis. 2010;7:181–7. DOIPubMedGoogle Scholar
  15. Cloeckaert  A, Praud  K, Lefevre  M, Doublet  B, Pardos  M, Granier  SA, IncI1 plasmid carrying extended-spectrum-β-lactamase gene blaCTX-M-1 in Salmonella enterica isolates from poultry and humans in France, 2003 to 2008. Antimicrob Agents Chemother. 2010;54:4484–6. DOIPubMedGoogle Scholar

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