Volume 18, Number 1—January 2012
Dispatch
Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model
Figure 1
![](/eid/images/11-1092-F1.jpg)
Figure 1. Western blot analysis of protease-resistant prion protein in the brain (thalamus/hypothalamus) and spleen of mouse lemurs inoculated with a cattle-derived L-type bovine spongiform encephalopathy (BSE) isolate by oral and intracerebral routes by using SHa31 monoclonal antibody against prion protein. Lanes 1, 7: cattle L-type BSE isolate (02-2528); lanes 2, 3: brain sample from intracerebral inoculation at 5 mg; lane 4: brain sample from oral inoculation at 50 mg; lanes 5, 6: brain sample from oral inoculation at 5 mg; lanes 8, 9: spleen samples from oral inoculation at 5 mg, positive and negative, respectively.
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