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Volume 18, Number 11—November 2012
Research

Community Outbreak of Adenovirus, Taiwan, 2011

Tsung-Pei Tsou1, Boon-Fatt Tan1, Hsin-Yu Chang1, Wan-Chin Chen, Yuan-Pin Huang, Chen-Yin Lai, Yen-Nan Chao, Sung-Hsi Wei, Min-Nan Hung, Li-Ching Hsu, Chun-Yi Lu, Pei-Lan Shao, Jung-Jung Mu, Luan-Yin Chang, Ming-Tsan LiuComments to Author , Li-Min Huang, and The Unknown Pathogen Discovery/Investigation Group
Author affiliations: Centers for Disease Control, Taipei, Taiwan (T.P. Tsou, W.C. Chen, Y.P. Huang, Y.N. Chao, S.H. Wei, M.N. Hung, L.C. Hsu, J.J. Mu, M.T. Liu); and National Taiwan University Hospital, Taipei (B.F. Tan, H.Y. Chang, C.Y. Lai, C.Y. Lu, P.L. Shao, L.Y. Chang, L.M. Huang)

Main Article

Table 3

Laboratory test results for 202 children hospitalized for adenovirus infection at National Taiwan University Hospital, by disease severity, Taipei City, Taiwan, November 2010–June 2011*

Laboratory results and no. patients tested All Severe infection, n = 31 Nonsevere infection, n = 171 p value
Hemoglobin, g/dL (range), n = 201 11.7 9.7 (3.4–13.8) 11.8 (7.0–14.6) <0.001
Platelets, × 103/μL (range), n = 201 237 106 (11–340) 251(14–555) <0.001

Thrombocytopenia, no. (%) patients†

 43 (21) 24 (77) 19 (11) <0.001
Leukocytes, × 103 cells/μL (range), n = 201 10.06 4.4 (1.2–10.3) 11.3 (0.2–35.5) <0.001

Leukopenia, no. (%) patients‡

 28 (14) 18 (58) 10 (6) <0.001
Sodium, mmol/L (range), n = 138 135 131 (119–137) 135 (127–142) <0.001
Hyponatremia, no. (%) patients§ 68 (49) 22 (81) 46 (41) <0.001
C-reactive protein, mg/dL (range), n = 200 4.15 6.1 (0.02–30.00) 4.0 (0–47.2) 0.086
LDH, U/L (range), n = 22 2,202 3,281 (1,029–9,782) 937 (493–17,454) 0.023
AST, U/L (range), n = 117 43 135 (38–3,520) 38 (3.5–989) <0.001

AST >2× upper limit, no. (%) patients

 36 (31) 22 (85) 14 (15) <0.001
ALT, U/L (range), n = 104 26.5 67.5 (12.0–511.0) 24 (8–652) <0.001

ALT >2× upper limit, no. (%) patients

 24 (23) 15 (58) 9 (12) <0.001
Creatinine, mg/dL (range), n = 155 0.61 0.68 (0.3–1.1) 0.6 (0.2–0.9) 0.088

*Severe infection indicates patients who were admitted to the intensive care unit. LDH, lactate dehydrogenase; AST, aspartate aminotransferase; ALT, alanine aminotransferase.
†Platelet count <150,000/μL.
‡Leukocyte count <5,000 cells/μL.
§Serum sodium <135 mmol/L.

Main Article

1These authors contributed equally to this article.

Page created: October 16, 2012
Page updated: October 16, 2012
Page reviewed: October 16, 2012
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