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Volume 18, Number 11—November 2012
Etymologia

Etymologia: Coxsackievirus

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Named for Coxsackie, the small town on the Hudson River where they were first isolated, human coxsackieviruses are nonenveloped, positive-sense, single-stranded RNA viruses in the family Picornaviridae, genus Enterovirus. They were first described by Gilbert Dalldorf, who was investigating suspected poliomyelitis outbreaks in upstate New York in the summer of 1947. Coxsackieviruses are divided into 2 groups, A and B. In suckling mice, group A viruses cause generalized myositis and flaccid paralysis, and group B viruses cause focal myositis and spastic paralysis. With the discovery of coxsackieviruses, Dalldorf also helped popularize the suckling mouse as an inexpensive laboratory animal model.

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References

  1. Dalldorf  G. The Coxsackie viruses. Bull N Y Acad Med. 1950;26:32935.PubMedGoogle Scholar
  2. Dalldorf  G, Sickles  GM, Plager  H. Gifford R. A virus recovered from the feces of “poliomyelitis” patients pathogenic for suckling mice. J Exp Med. 1949;89:56782. DOIPubMedGoogle Scholar
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  4. Racaniello  V. Coxsackie NY and the virus named after it, August 10, 2009 [cited 2012 Aug 21]. http://www.virology.ws/2009/08/10/coxsackie-ny-and-the-virus-named-after-it/
  5. Tao  Z, Song  Y, Li  Y, Liu  Y, Jiang  P, Lin  X, Coxsackievirus B3, Shandong Province, China, 1990–2010. Emerg Infect Dis. 2012;18:18657. DOIGoogle Scholar

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Cite This Article

DOI: 10.3201/eid1811.et1811

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Table of Contents – Volume 18, Number 11—November 2012

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Page created: October 12, 2012
Page updated: October 12, 2012
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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