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Volume 18, Number 12—December 2012

West Nile Virus Neurologic Disease in Humans, South Africa, September 2008–May 2009

Dewald Zaayman and Marietjie VenterComments to Author 
Author affiliations: Author affiliations: University of Pretoria, Pretoria, South Africa (D. Zaayman, M. Venter); National Institute for Communicable Diseases, Johannesburg, South Africa (M. Venter)

Main Article

Table 1

Characteristics and clinical information for 7 acutely ill patients with WNV infection, South Africa*

Sample no. Date sample collected Patient age, y/sex Sample type WNV antigen/antibody test
Clinical information
AN (titer) IgM PCR
4562 2008 Nov 45/M CSF Pos (4) Suspected HIV encephalopathy or PML, TPHA neg, HIV neg, paraparesis
6208 2008 Nov 35/F CSF Pos (4) Hepatomegaly, lymphadenopathy, fever, vomiting, epigastric pain, EBV IgM neg, EBV IgG pos, malaria neg, hepatitis neg
8785 2009 Jan 36/M CSF Pos (4) Acute paresis of lower limbs, delirium, HSV-1 and HSV-2 neg (PCR), HTLV-1 neg, TPHA neg
3111 2009 Feb 5/M CSF Pos (4) Meningitis, enterovirus pos (PCR)
0269 2009 Apr 11/M Serum Pos (40) Pos Neg Rash, fever, Brucella neg (PCR), coxsackieviruses B1–B6 neg, CMV IgM neg, CMV IgG pos
0312 2009 Apr 26/M Serum Pos (80) Pos Neg Severe headache, fever, suspected enterovirus, coxsackieviruses B1–B5 neg, Rickettsia conorii neg, EBV IgM neg
SAH 5238 2008 Oct 2/M CSF Neg Neg Pos Decreased level of consciousness, rash, fever, meningitis, measles neg, mumps neg

*WNV, West Nile virus; AN, antibody neutralization; CSF, cerebrospinal fluid; pos, positive; –, insufficient sample for testing; PML, progressive multifocal leukoencephalopathy; TPHA, Treponema pallidum hemagglutination assay; neg, negative; EBV, Epstein-Barr virus; HSV-1 and -2, herpes simplex virus types 1 and 2; HTLV, human T-lymphotropic virus; CMV, cytomegalovirus.

Main Article

Page created: November 20, 2012
Page updated: November 20, 2012
Page reviewed: November 20, 2012
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