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Volume 18, Number 12—December 2012
CME ACTIVITY - Dispatch

Enterovirus 71–associated Hand, Foot, and Mouth Disease, Southern Vietnam, 2011

Truong Huu Khanh, Saraswathy Sabanathan, Tran Tan Thanh, Le Phan Kim Thoa, Tang Chi Thuong, Vu thi Ty Hang, Jeremy Farrar, Tran Tinh Hien, Nguyen van Vinh Chau, and H. Rogier van DoornComments to Author 
Author affiliations: Author affiliations: Children’s Hospital 1, Ho Chi Minh City, Vietnam (T.H. Khanh, L.P.K. Thoa, T.C. Thuong); Oxford University Clinical Research Unit, Oxford, UK (S. Sabanathan, T.T. Thanh, V.t.T. Hang, J. Farrar, T.T. Hien, H.R. van Doorn); Oxford University (S. Sabanathan, J. Farrar, T.T. Hien, H.R. van Doorn); Hospital for Tropical Diseases, Ho Chi Minh City (N.v.V. Chau)

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Figure 2

Phylogenetic tree of enterovirus 71 viral protein 1 constructed by MEGA4 (www.megasoftware.net) with neighbor-joining method showing the relationship of 18 local sequences from 2010 and 2011 (triangles). Sequence names consist of the following information: the hospital at which the sample was obtained (HTD, Hospital for Tropical Diseases; CH1, Children’s Hospital 1; CH2, Children’s Hospital 2 (all from Ho Chi Minh City, Vietnam]); number in chronologic order/VNM for Vietnam/date (month-year). Re

Figure 2. . . Phylogenetic tree of enterovirus 71 viral protein 1 constructed by MEGA4 (www.megasoftware.net) with neighbor-joining method showing the relationship of 18 local sequences from 2010 and 2011 (triangles). Sequence names consist of the following information: the hospital at which the sample was obtained (HTD, Hospital for Tropical Diseases; CH1, Children’s Hospital 1; CH2, Children’s Hospital 2 (all from Ho Chi Minh City, Vietnam]); number in chronologic order/VNM for Vietnam/date (month-year). Reference genotypic sequences used in tree construction were obtained from GenBank. Detailed information about these sequences is available in reference (1).

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References
  1. Tu  PV, Thao  NT, Perera  D, Huu  TK, Tien  NT, Thuong  TC, Epidemiologic and virologic investigation of hand, foot, and mouth disease, southern Vietnam, 2005. Emerg Infect Dis. 2007;13:1733–41. DOIPubMedGoogle Scholar
  2. Mizuta  K, Abiko  C, Murata  T, Matsuzaki  Y, Itagaki  T, Sanjoh  K, Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003. J Clin Microbiol. 2005;43:6171–5. DOIPubMedGoogle Scholar
  3. Ooi  MH, Wong  SC, Podin  Y, Akin  W, del Sel  S, Mohan  A, Human enterovirus 71 disease in Sarawak, Malaysia: a prospective clinical, virological, and molecular epidemiological study. Clin Infect Dis. 2007;44:646–56. DOIPubMedGoogle Scholar
  4. World Health Organization. Hand, foot and mouth disease situation update, 9 August 2012. [cited 2012 Aug 10]. http://www.wpro.who.int/emerging_diseases/HFMD/en/index.html
  5. Huang  CC, Liu  CC, Chang  YC, Chen  CY, Wang  ST, Yeh  TF. Neurologic complications in children with enterovirus 71 infection. N Engl J Med. 1999;341:936–42. DOIPubMedGoogle Scholar
  6. Beld  M, Minnaar  R, Weel  J, Sol  C, Damen  M, van der Avoort  H, Highly sensitive assay for detection of enterovirus in clinical specimens by reverse transcription–PCR with an armored RNA internal control. J Clin Microbiol. 2004;42:3059–64. DOIPubMedGoogle Scholar
  7. Thao  NT. Hand, foot and mouth disease—Viet Nam (03): Ho Chi Minh City. ProMed. 2011 Jun 6 [cited 2012 Aug 1]. http://www.promedmail.org, archive no. 20110607.1739.
  8. Lin  KH, Hwang  KP, Ke  GM, Wang  CF, Ke  LY, Hsu  YT, Evolution of EV71 genogroup in Taiwan from 1998 to 2005: an emerging of subgenogroup C4 of EV71. J Med Virol. 2006;78:254–62. DOIPubMedGoogle Scholar
  9. McWilliam Leitch  EC, Cabrerizo  M, Cardosa  J, Harvala  H, Ivanova  OE, Koike  S, The association of recombination events in the founding and emergence of subgenogroup evolutionary lineages of human enterovirus 71. J Virol. 2012;86:2676–85. DOIPubMedGoogle Scholar
  10. Tee  KK, Lam  TT, Chan  YF, Bible  JM, Kamarulzaman  A, Tong  CY, Evolutionary genetics of human enterovirus 71: origin, population dynamics, natural selection, and seasonal periodicity of the VP1 gene. J Virol. 2010;84:3339–50. DOIPubMedGoogle Scholar
  11. Mizuta  K, Aoki  Y, Suto  A, Ootani  K, Katsushima  N, Itagaki  T, Cross-antigenicity among EV71 strains from different genogroups isolated in Yamagata, Japan, between 1990 and 2007. Vaccine. 2009;27:3153–8. DOIPubMedGoogle Scholar
  12. Tran  CB, Nguyen  HT, Phan  HT, Tran  NV, Wills  B, Farrar  J, The seroprevalence and seroincidence of enterovirus71 infection in infants and children in Ho Chi Minh City, Viet Nam. PLoS ONE. 2011;6:e21116. DOIPubMedGoogle Scholar
  13. Lu  CY, Lee  CY, Kao  CL, Shao  WY, Lee  PI, Twu  SJ, Incidence and case-fatality rates resulting from the 1998 enterovirus 71 outbreak in Taiwan. J Med Virol. 2002;67:217–23. DOIPubMedGoogle Scholar

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