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Volume 18, Number 2—February 2012

Letter

Zika Virus Infection, Cambodia, 2010

Vireak Heang, Chadwick Y. Yasuda, Ly Sovann, Andrew D. Haddow, Amelia P Travassos da Rosa, Robert B. Tesh, and Matthew R. Kasper1Comments to Author 
Author affiliations: US Naval Medical Research Unit No. 2, Phnom Penh, Cambodia (V. Heang, C.Y. Yasuda); Ministry of Health, Phnom Penh (L. Sovann); University of Texas Medical Branch, Galveston, Texas, USA (A.D. Haddow, A.P. Travassos da Rosa, R.B. Tesh); US Naval Medical Research Unit No. 2, Jakarta, Indonesia (M.R. Kasper)

Main Article

Table

Reported or observed clinical signs and symptoms in persons with Zika virus infection, 1962–2010

Sign or symptom Country, year of infection origin,* no. (%) patients
Uganda, 1962, n = 1 Laboratory acquired, 1973, n = 1 Indonesia,
1977–1978, n = 7 Micronesia, 2007, n = 28 Senegal/United States, 2009, n = 3 Cambodia, 2010, n = 1
Fever 1 (100) 1 (100) 7 (100) 20 (65) 1 (100)
Headache 1 (100) 14 (45) 3 (100) 1 (100)
Malaise 1 (100) 5 (71) 3 (100)
Maculopapular rash 1 (100) 28 (100) 3 (100)
Fatigue or myalgia 1 (100) 1 (100) 1 (14) 14 (45) 1 (33)
Arthritis and arthralgia 1 (14) 20 (65) 3 (100)
Chills 1 (100) 2 (29) 2 (67)
Dizziness 5 (71)
Joint swelling or edema 6 (19) 2 (67)
Stomachache 6 (86)
Retro-orbital pain 1 (100) 12 (39)
Conjunctivitis 1 (14) 17 (55) 1 (33)
Anorexia 4 (57)
Photophobia 1 (33)
Vomiting 1 (14) 3 (10)
Diarrhea 3 (43)
Constipation 3 (43)
Sore throat 1 (100)
Cough 1 (100)
Aphthous ulcer 2 (67)
Hypotension 2 (29)
Hematuria 1 (14)
Prostatitis 1 (33)
Hematospermia 1 (33)
Sweating 1 (100)
Lightheadedness 1 (33)

*References: Uganda (2), laboratory-acquired (10), Indonesia (5), Micronesia (9), Senegal/United States (4). Blank cells indicate no reported information.

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References
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1Current affiliation: US Naval Medical Research Unit No. 6, Lima, Peru.

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