Volume 18, Number 2—February 2012
Research
Association of Human Bocavirus 1 Infection with Respiratory Disease in Childhood Follow-up Study, Finland
Table 1
Human bocavirus IgG results from 109 constitutionally healthy children, Finland
Result* | No. (%) | Age, y |
||
---|---|---|---|---|
Mean | Median | Range | ||
Seroconversion | 102 (94) | 2.30 | 2.08 | 0.31–6.00 |
Secondary response† | 38 (35) | 4.79 | 4.77 | 0.73–9.79 |
Reconversion | 7 (6) | 6.29 | 7.07 | 1.59–8.15 |
*Maternal antibodies, i.e., low-level (vanishing) IgG, were detected in 35/88 children from whom serum was taken ≤6 mo. of age. Seven children were IgG positive from birth, and their maternal antibodies were not seen to disappear before induction of their own immunity. For 73, the IgG level remained high; for 26, the IgG level decreased with time; and 10 underwent IgG reversion.
†>4-fold increase in, or reconversion of, high avidity IgG (2 children had 2 and 2 other children had 3 secondary immune responses).