Volume 18, Number 6—June 2012
Research
Intrafamilial Circulation of Tropheryma whipplei, France
Florence Fenollar, Alpha K. Keita, Sylvain Buffet, and Didier Raoult
Table 1
Results of Tropheryma whipplei PCR on 74 relatives from 21 families of patients with classic Whipple disease, localized T. whipplei chronic infection, or asymptomatic carriers, France, 2003–2011
| T. whipplei | No. relatives (no. families) | No. female relatives | Age, all patients (mean ± SD) | No. samples PCR positive/no. tested (%) |
||
|---|---|---|---|---|---|---|
| Feces | Saliva | Feces or saliva | ||||
| Overall | 74 (21) | 40 | 2 mo–79 y (38 y ± 22 y) | 24/64 (38) | 7/70 (10) | 25/74 (34) |
| Classic Whipple disease | 50 (13) | 29 | 2 mo–79 y (38.8 y ± 22 y) | 14/45 (31) | 4/48 (8) | 14/50 (28) |
| Localized infection | 14 (5) | 5 | 7–75 y (40.7 y ± 24.9 y) | 2/9 (22) | 1/12 (8) | 3/14 (21) |
| Carrier | 10 (3) | 6 | 8–65 y (29.6 y ± 21.1 y) | 8/10 (80) | 2/10 (20) | 8/10 (80) |
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