Volume 18, Number 6—June 2012
Research
Intrafamilial Circulation of Tropheryma whipplei, France
Table A1
Results of Tropheryma whipplei Western blot serologic analysis for 30 relatives of 2 T. whipplei carriers, 8 patients with classic Whipple disease, and 3 patients with localized infections and their T. whipplei PCR results, France, 2003–2011*
Infection status |
Age, y/sex |
Immune response |
Relative, T. whipplei PCR results, and immune response |
|||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Relative 1 | Relative 2 | Relative 3 | Relative 4 | Relative 5 | ||||||||||||
Relationship/age, y |
Feces/saliva/ immune response |
Relationship/age, y |
Feces/saliva/immune response |
Relationship/age, y |
Feces/saliva/immune response |
Relationship/age, y |
Feces/saliva/immune response |
Relationship/age, y |
Feces/saliva/immune response |
|||||||
Carrier | ||||||||||||||||
Carrier 1 | 47/M | Strong | Wife/41 | +/–/strong | Son 1/12 | +/+/strong | Son 2/12 | +/–/strong | ||||||||
Carrier 2 | 35/M | Strong | Wife/29 | +/–/strong | - | |||||||||||
Classic Whipple disease | ||||||||||||||||
Patient 1 | 40/F | Deficient | Father/71 | +/+/strong | Mother/70 | +/–/strong | ||||||||||
Patient 2 | 58/M | Deficient | Wife/60 | –/–/strong | Daughter/32 | +/+/strong | ||||||||||
Patient 3 | 48/M | Deficient | Wife/51 | +/–/strong | Son/22 | +/–/strong | ||||||||||
Patient 4 | 35/M | Deficient | Father/NA | –/–/deficient | Mother/NA | –/–/deficient | ||||||||||
Patient 5 | 26/F | Deficient | Father/57 | –/–/strong | Mother/55 | +/–/strong | ||||||||||
Patient 6 | 62/M | Deficient | Wife/62 | –/–/strong | ||||||||||||
Patient 7 | 43/M | Deficient | Wife/45 | –/–/deficient | Son/20 | +/+/deficient | Daughter/18 | +/–/deficient | ||||||||
Patient 8 | 75/M | Deficient | Wife/71 | NA/–/strong | - | |||||||||||
Patient 9 | 39/F | Deficient | Husband/42 | +/–/strong | Brother/50 | +/+/strong | Mother/76 | –/–/deficient | Father/77 | +/–/deficient | Sister/52 | +/–/strong | ||||
Localized infection | ||||||||||||||||
Patient 10 | 36/M | Deficient | Wife/43 | NA/–/strong | Son/12 | NA/+/strong | ||||||||||
Patient 11 | 71/F | Deficient | Husband/73 | +/–/strong | ||||||||||||
Patient 12 | 55/F | Strong | Husband/53 | –/–/strong | Mother/75 | –/–/strong | Half aunt/56 | –/NA/strong |
*+, positive; –, negative; NA, not available. Blank cells indicate no additional relatives.