Volume 18, Number 6—June 2012
Research
Intrafamilial Circulation of Tropheryma whipplei, France
Florence Fenollar, Alpha K. Keita, Sylvain Buffet, and Didier Raoult
Table A1
Results of Tropheryma whipplei Western blot serologic analysis for 30 relatives of 2 T. whipplei carriers, 8 patients with classic Whipple disease, and 3 patients with localized infections and their T. whipplei PCR results, France, 2003–2011*
| Infection status |
Age, y/sex |
Immune response |
Relative, T. whipplei PCR results, and immune response |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Relative 1 | Relative 2 | Relative 3 | Relative 4 | Relative 5 | ||||||||||||
| Relationship/age, y |
Feces/saliva/ immune response |
Relationship/age, y |
Feces/saliva/immune response |
Relationship/age, y |
Feces/saliva/immune response |
Relationship/age, y |
Feces/saliva/immune response |
Relationship/age, y |
Feces/saliva/immune response |
|||||||
| Carrier | ||||||||||||||||
| Carrier 1 | 47/M | Strong | Wife/41 | +/–/strong | Son 1/12 | +/+/strong | Son 2/12 | +/–/strong | ||||||||
| Carrier 2 | 35/M | Strong | Wife/29 | +/–/strong | - | |||||||||||
| Classic Whipple disease | ||||||||||||||||
| Patient 1 | 40/F | Deficient | Father/71 | +/+/strong | Mother/70 | +/–/strong | ||||||||||
| Patient 2 | 58/M | Deficient | Wife/60 | –/–/strong | Daughter/32 | +/+/strong | ||||||||||
| Patient 3 | 48/M | Deficient | Wife/51 | +/–/strong | Son/22 | +/–/strong | ||||||||||
| Patient 4 | 35/M | Deficient | Father/NA | –/–/deficient | Mother/NA | –/–/deficient | ||||||||||
| Patient 5 | 26/F | Deficient | Father/57 | –/–/strong | Mother/55 | +/–/strong | ||||||||||
| Patient 6 | 62/M | Deficient | Wife/62 | –/–/strong | ||||||||||||
| Patient 7 | 43/M | Deficient | Wife/45 | –/–/deficient | Son/20 | +/+/deficient | Daughter/18 | +/–/deficient | ||||||||
| Patient 8 | 75/M | Deficient | Wife/71 | NA/–/strong | - | |||||||||||
| Patient 9 | 39/F | Deficient | Husband/42 | +/–/strong | Brother/50 | +/+/strong | Mother/76 | –/–/deficient | Father/77 | +/–/deficient | Sister/52 | +/–/strong | ||||
| Localized infection | ||||||||||||||||
| Patient 10 | 36/M | Deficient | Wife/43 | NA/–/strong | Son/12 | NA/+/strong | ||||||||||
| Patient 11 | 71/F | Deficient | Husband/73 | +/–/strong | ||||||||||||
| Patient 12 | 55/F | Strong | Husband/53 | –/–/strong | Mother/75 | –/–/strong | Half aunt/56 | –/NA/strong | ||||||||
*+, positive; –, negative; NA, not available. Blank cells indicate no additional relatives.
Page created: May 11, 2012
Page updated: May 11, 2012
Page reviewed: May 11, 2012
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