Volume 18, Number 6—June 2012
Research
Intrafamilial Circulation of Tropheryma whipplei, France
Florence Fenollar, Alpha K. Keita, Sylvain Buffet, and Didier Raoult
Table 3
Arguments for and against the intrafamilial transmission of Tropheryma whipplei, France, 2003–2011
| Argument in favor | Argument against |
|---|---|
| Epidemiologic | |
| T. whipplei carriage is significantly more common in persons related by genetics and marriage (34%) than in the general population of France (2%–4%) | Presence of few different bacterial genotypes in some families |
| Significant detection of the same bacterial genotypes in most families | |
| Most persons did not live in the same household and had contact only during family gatherings in different places | |
| Microbiologic | |
| Positive serologic results in relatives (77%) significantly higher than in the general population of France (48%) |
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