Volume 18, Number 8—August 2012
Dispatch
Seroprevalence and Cross-reactivity of Human Polyomavirus 9
Table
Cross-competition between HPyV9, LPyV, and MCPyV VP1 in serum samples reactive against HPyV9 and LPyV VP1 virus-like particles*
Serum sample no. | HPyV9 reactivity (OD) after preincubation with |
LPyV reactivity (OD) after preincubation with |
|||||||
---|---|---|---|---|---|---|---|---|---|
Control | HPyV9 | LPyV | MCPyV | Control | HPyV9 | LPyV | MCPyV | ||
H1 | 0.988 | 0.054 | 0.737 | 0.943 | 0.848 | 0.049 | 0.036 | 0.841 | |
H2 | 1.083 | 0.128 | 0.737 | 1.018 | 1.007 | 0.128 | 0.104 | 0.995 | |
H3 | 1.154 | 0.100 | 0.921 | 1.128 | 1.080 | 0.073 | 0.061 | 1.159 | |
H4 | 2.147 | 0.164 | 1.308 | 1.869 | 1.680 | 0.126 | 0.100 | 1.629 | |
H5 | 2.256 | 0.195 | 2.023 | 2.152 | 2.525 | 0.349 | 0.153 | 2.671 | |
H6 | 1.610 | 0.127 | 0.846 | 1.544 | 2.068 | 0.099 | 0.095 | 2.179 | |
H7 | 1.223 | 0.088 | 0.577 | 1.456 | 1.816 | 0.069 | 0.062 | 1.828 | |
H8 | 1.136 | 0.017 | 0.629 | 0.935 | 0.599 | 0.015 | 0.162 | 0.545 | |
H9 | 0.732 | 0.055 | 0.437 | 0.648 | 0.441 | 0.119 | 0.075 | 0.448 | |
H10 | 1.216 | 0.036 | 0.683 | 1.057 | 0.771 | 0.045 | 0.032 | 0.659 | |
H11 | 1.489 | 0.070 | 1.114 | 1.303 | 0.801 | 0.203 | 0.070 | 0.522 | |
H12 | 1.406 | 0.016 | 0.776 | 1.265 | 0.885 | 0.041 | 0.032 | 0.858 | |
H13 | 1.682 | 0.042 | 0.944 | 1.199 | 0.853 | 0.168 | 0.065 | 0.547 | |
H14 | 2.424 | 0.061 | 1.566 | 2.145 | 1.536 | 0.064 | 0.058 | 1.516 | |
H15 | 2.843 | 0.067 | 2.109 | 2.611 | 2.339 | 0.075 | 0.318 | 2.205 |
*HPyV9, human polyomavirus 9; LPyV, simian lymphotropic polyomavirus; MCPyV, Merkel cell polyomavirus; VP1, viral protein 1; OD, optical density. Fifteen serum samples from blood donors reactive against HPyV9 and LPyV VP1 virus-like particles were preincubated with HPyV9, LPyV, or MCPyV VLPs.