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Volume 18, Number 8—August 2012

Population Diversity among Bordetella pertussis Isolates, United States, 1935–2009

Amber J. Schmidtke, Kathryn O. Boney, Stacey W. Martin, Tami H. Skoff, M. Lucia Tondella, and Kathleen M. TattiComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article


Diversity trends among selected Bordetella pertussis isolates, United States, 1935–2009*

Study period Years Vaccine use Simpson diversity index, % (95% CI)
1 1935–1945 Pre-wP 66.7 (30.4–103.0)
2 1946–1969 Early-wP 77.8 (59.4–96.2)
3 1970–1990 Late-wP 94.0 (90.9–97.1)
4 1991–1996 wP/aP transition (4th–5th doses) 75.7 (65.9–85.5)
5 1997–1999 Early-aP 66.8 (59.5–74.1)
6 2000–2002 Mid-aP 70.2 (67.7–81.1)
7 2003–2005 Late-aP 71.6 (62.4–80.8)
8 2006–2009 Tdap 69.3 (60.7–77.9)

*wP, whole cell vaccine; aP, acellular vaccine; Tdap, tetanus-diphtheria-aP.

Main Article

Page created: July 19, 2012
Page updated: July 19, 2012
Page reviewed: July 19, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.