Volume 18, Number 8—August 2012
Peer Reviewed Report Available Online Only
Infectious Disease Transmission during Organ and Tissue Transplantation
Melissa A. Greenwald
, Matthew J. Kuehnert, and Jay A. Fishman
, Matthew J. Kuehnert, and Jay A. Fishman
Table 3
Key research factors and needs for organ and tissue transplant–associated infections
| Factor | Need |
|---|---|
| Denominator data | Tissue transplantation: number and type of allografts transplanted |
| Discard rate: number of donors rejected for organ and tissue transplantation because of identified donor risk | |
| Transmissibility data | Preclinical: animal studies, studies of unused organs, or tissues from infected donors |
| Clinical studies: outcomes from increased risk organ donors | |
| Risk mitigation strategies | Processing: tissue processing, pump perfusion of organs |
| Effects of antimicrobial agents: in organ donors, in organ or tissue recipients | |
| Donor questionnaire | Effectiveness of questions for obtaining accurate answers and for identifying donors with higher likelihood of having a positive test result |
| Research infrastructure | Organized network: to collect, share, and analyze data in organ and tissue transplantation |
| Harmonization: product names, label information, data collection methods, data sharing mechanisms | |
| Risk assessment | Use of data: model risks, further refine research needs |
| Quality improvement: evaluate effectiveness of changes, refine models for use with emerging diseases |
Page created: July 11, 2012
Page updated: July 11, 2012
Page reviewed: July 11, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
Content Credential