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Volume 18, Number 8—August 2012

Online Report

Peer Reviewed Report Available Online Only

Infectious Disease Transmission during Organ and Tissue Transplantation

Melissa A. GreenwaldComments to Author , Matthew J. Kuehnert, and Jay A. Fishman
Author affiliations: Food and Drug Administration, Rockville, Maryland, USA (M.A. Greenwald); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.J. Kuehnert); Massachusetts General Hospital, Boston, Massachusetts, USA (J.A. Fishman); and Harvard Medical School, Boston (J.A. Fishman)

Main Article

Table 1

Factors involved in transmission of infection by human allografts

Factor Specific feature
Organism Incidence, virulence, tissue tropism
Host Immune status, prior immunity, general health
Graft Organism incidence, viability, receptors for organisms, processing
Medical staff Clinical experience, laboratory technical support, comprehension of assay characteristics
Epidemiology Donor exposures (outbreaks, nosocomial, vectors, animals)

Main Article