Volume 19, Number 1—January 2013
Research
Seroepidemiologic Effects of Influenza A(H1N1)pdm09 in Australia, New Zealand, and Singapore
Table 5
Multivariate logistic regression models comparing specific collections on outcome of seropositivity, with exposures of region, age group, and sex, in community-based studies of influenza A (H1N1) 2009 in the Southern Hemisphere, winter 2009*
Collections compared |
No. assays included | Characteristics of model |
ORs (95% CIs) for exposure variables |
|||||
---|---|---|---|---|---|---|---|---|
Comp. | Ref. | Restrictions to inclusion | Rationale | Male sex | Age† | Comp. group/study compared with ref. group/study | ||
K | N | 493 | Residence in NSW; post; age 16–78 y | Stored pathology specimens survey vs. survey of blood donors (NSW) | 0.98 (0.65–1.49); p = 0.93 | 0.74 (0.66–0.84); p<0.001 | 1.37 (0.89–2.09); p = 0.15 | |
R | N | 204 | Residence in WA; post | Patients voluntarily enrolled in RCT vs. blood donors (WA) | 1.05 (0.56–1.98); p = 0.88 | 1.06 (0.86–1.31) p = 0.56 | 1.48 (0.79–2.79); p = 0.22 | |
D | K | 278 | Pre; age ≥58 y | Persons in res. care vs. community control group (NSW) | 0.49 (0.31–0.79); p = 0.003 | 2.79 (2.01–3.86); p<0.001 | 0.34 (0.15–0.79); p = 0.01 | |
M | K | 278 | Post; age 19–77 y | Persons with HIV infection vs. community control group (NSW) | 1.43 (0.80–2.57); p = 0.23 | 0.74 (0.61–0.90); p = 0.003 | 1.26 (0.66–2.41); p = 0.48 | |
Q | K | 192 | Post; age 43–88 y | Hemo. patients vs. community control group (NSW) | 0.90 (0.42–1.95); p = 0.79 | 0.91 (0.68–1.21); p = 0.50 | 1.65 (0.75–3.63); p = 0.21 | |
J | N, R | 316 | Res. in WA; post; age 21–45 y | Preg. women vs. community control group (WA) | . | 0.72 (0.48–1.06); p = 0.10 | 0.44 (0.24–0.81); p = 0.008 | |
C | B | 1,316 | Post; age >21 | HCWs vs. community control group (NZ) | 0.92 (0.70–1.22); p = 0.56 | 0.95 (0.88–1.03); p = 0.26 | 1.09 (0.83–1.42); p = 0.54 | |
F | E | 1,080 | Post | HCWs vs. community control group (Sing.) | 1.12 (0.74–1.71); p = 0.59 | 0.78 (0.66–0.93); p = 0.006 | 0.65 (0.41–1.01); p = 0.06 | |
H | E | 996 | Post; age 21–62 | Military personnel vs. community control group (Sing.) | 1.19 (0.75–1.88); p = 0.45 | 0.71 (0.58 – 0.85); p<0.001 | 0.97 (0.58–1.60); p = 0.89 | |
G | E | 858 | Post | Res. care group vs. community control group (Sing.) | 1.38 (0.89–2.16); p = 0.15 | 0.81 (0.68–0.96); p= 0.02 | 0.44 (0.22–0.90); p = 0.03 | |
P | P | 1,689 | Post | Aboriginal and Torres Strait Islanders vs. nonindig. people (NT) | 0.95 (0.74–1.22); p = 0.68 | 0.88 (0.82–0.94); p<0.001 | 2.67 (2.08–3.42); p<0.001 | |
B | B | 1,147 | Post | Maori vs nonindig. people (NZ) | 0.95 (0.73–1.22); p = 0.66 | 0.86 (0.82–0.91); p <0.001 | 1.17 (0.83–1.64); p = 0.38 | |
B | B | 966 | Post | Pacific Peoples vs. nonindig. people (NZ) | 1.04 (0.78–1.37); p = 0.80 | 0.87 (0.82–0.92);p<0.001 | 1.99 (1.41–2.82); p<0.001 |
*ORs, odds ratios; comp., comparison; ref., referent; NSW, New South Wales; post, postpandemic phase; WA, Western Australia; RCT, randomized controlled trial; pre, prepandemic phase; res., residence/residential; hemo., hemodialysis; preg., pregnant; HCWs, health care workers; NZ, New Zealand; NT, Northern Territory; nonindig., nonindigenous. The 13 regression models are displayed horizontally.
†Age considered a continuous variable with OR for each decade of increasing age.
1A list of the group’s members can be found at the end of this article.