Volume 19, Number 11—November 2013
Dispatch
Full Genome of Influenza A (H7N9) Virus Derived by Direct Sequencing without Culture
Xianwen Ren1, Fan Yang1, Yongfeng Hu1, Ting Zhang1, Liguo Liu1, Jie Dong, Lilian Sun, Yafang Zhu, Yan Xiao, Li Li, Jian Yang, Jianwei Wang, and Qi Jin
Table 1
Mutations of directly sequenced influenza A (H7N9) virus and that obtained from chicken egg culture*
| Gene | Position | Direct sequencing | Chicken egg culture | Amino acid change |
|---|---|---|---|---|
| PB2 | 18 | A | G | Synonymous |
| PB2 | 1601 | C | T | S534F |
| PB1 | 303 | G | A | Synonymous |
| PB1 | 825 | G | A | Synonymous |
| PB1 | 2274 | A | G | Synonymous |
| PA | 2115 | G | T | Synonymous |
| PA | 2119 | G | T | V707F |
| PA | 2127 | A | C | Synonymous |
| NS | 176 | G | A | R59H in NS1 |
| NS | 792 | C | T | P107L in NS2 |
| NS | 803 | G | C | Synonymous |
| NS | 804 | T | A | Synonymous |
| NS | 805 | C | A | V111Q in NS2 |
| NP | 387 | A | T | Synonymous |
| NP | 438 | T | C | Synonymous |
| NP | 480 | T | C | Synonymous |
| NP | 648 | A | G | Synonymous |
| NP | 657 | T | C | Synonymous |
| NP | 663 | A | G | Synonymous |
| NP | 892 | T | C | Synonymous |
| NP | 962 | G | A | S321N |
| NP | 982 | C | T | Synonymous |
| NP | 1086 | G | A | Synonymous |
| NP | 1113 | G | A | M371I |
| NP | 1200 | G | A | Synonymous |
| NP | 1251 | C | T | Synonymous |
| NP | 1257 | T | C | Synonymous |
| NP |
1440 |
T |
C |
Synonymous |
| *PB, polymerase basic; PA, polymerase acidic; NS, nonstructural; NP, nucleocapsid protein. | ||||
1These authors contributed equally to this article.
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Page updated: October 29, 2013
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