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Volume 19, Number 3—March 2013

Clinical and Therapeutic Features of Pulmonary Nontuberculous Mycobacterial Disease, Rio de Janeiro, Brazil

Karla Gripp Couto de Mello, Fernanda C.Q. Mello, Liamar Borga, Valeria Rolla, Rafael S. Duarte, Elizabeth P. Sampaio, Steven M. Holland, D. Rebecca Prevots, and Margareth P. DalcolmoComments to Author 
Author affiliations: Author affiliations: National School of Public Heath, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil (K.G.C. de Mello, L. Borga, M.P. Dalcolmo); School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro (F.Q. Mello); Oswaldo Cruz Institute, Rio de Janeiro (V. Rolla, E.P. Sampaio); Federal University of Rio de Janeiro (R.S. Duarte); and National Institutes of Health, Bethesda, Maryland, USA (S.M. Holland, D.R. Prevots)

Main Article

Table 1

Demographic and clinical features for patients with PNTM, Rio de Janeiro, Brazil, 1993– 2011*

Characteristic No. (%) patients
Male sex 108 (62.1)
Age, median y (range)
55 (24–86)†
Past or current smoker‡
95 (62.1)
Clinical findings
Respiratory symptoms only 106 (60.9)
Fever and weight loss 15 (8.6)
Respiratory and systemic symptoms 
(fever, weight loss)
53 (30.5)
Previous TB treatment
Treated previously for TB 101 (58)
Referred while being treated for TB
80 (79)
Radiology results (lesion type)
Cavitary disease 118 (67.8)
56 (32.2)
Median duration of treatment, mo (range)
19 (2–36)†
ATS microbiologic criteria
1 positive sputum culture 47 (27)
>2 positive sputum cultures
101 1 (58)
Bronchoalveolar lavage 24 (13.8)
Lung biopsy 2 (1.1))

*PNTM, pulmonary nontuberculous mycobacterial disease; TB, tuberculosis; ATS, American Thoracic Society.
†Data are as indicated in the left column.
‡Smoking data were missing for 21 patients.

Main Article

Page created: February 13, 2013
Page updated: February 22, 2013
Page reviewed: February 22, 2013
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