Volume 19, Number 3—March 2013
CME ACTIVITY - Research
Clinical and Therapeutic Features of Pulmonary Nontuberculous Mycobacterial Disease, Rio de Janeiro, Brazil
Karla Gripp Couto de Mello, Fernanda C.Q. Mello, Liamar Borga, Valeria Rolla, Rafael S. Duarte, Elizabeth P. Sampaio, Steven M. Holland, D. Rebecca Prevots, and Margareth P. Dalcolmo
Table 6
Treatment regimens for all patients with ATS-defined PNTM, per infecting species, Brazil, 1993–2011*
| Species | Treatment regimen (%)† |
|---|---|
| Mycobacterium avium complex | Clarithromycin, amikacin,ethambutol, rifampin (54.7) |
| Clarithromycin, ethambutol,quinolone, terizidon (28.3) | |
| Clarithromycin, amikacin, ethambutol, quinolone‡ (17.0) |
|
| Mycobacterium kansasii | Rifampin, ethambutol, isoniazid (52.5) |
| Rifampin, ethambutol, isoniazid, clarithromycin, amikacin (47.5) |
|
| M. abscessus | Clarithromycin, amikacin (68.4) |
| Clarihromycin, amikacin, doxycycline (10.5) | |
| Clarithromycin, amikacin, terizidon (21) |
|
| M. massiliense | Clarithromycin, amikacin (33.3) |
| Clarithromycin, amikacin, terizidon (33.3) | |
| Clarithromycin, amikacin, imipenem, tigeciclin (33.3) |
|
| M. fortuitum | Clarithromycin, amikacin, quinolone (64.2) |
| Clarithromycin, amikacin, terizidon (28.5) | |
| Clarithromycin, amikacin, quinolone, doxycycline (7.3) |
*ATS, AmericanThoracic Society; PNTM, pulmonary nontuberculous mycobacterial disease.
†Median duration of treatment, 19 mo.
‡Quinolones: levofloxacin, ciprofloxacin, moxifloxacin, ofloxacin.
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Page updated: February 22, 2013
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