Volume 19, Number 3—March 2013
Research
Treatment Outcomes for Extensively Drug-Resistant Tuberculosis and HIV Co-infection
Table 3
Predictor | No. died/total no. (%) | Univariate analysis |
Multivariate analysis† |
|||
---|---|---|---|---|---|---|
Hazard ratio (95% CI) | p value | Hazard ratio (95% CI) | p value | |||
Sex | ||||||
F | 27/65 (41.5) | 0.88 (0.50–1.54) | 0.6484 | 0.95 (0.51–1.77) | 0.8611 | |
M |
22/49 (44.9) |
1.0 (referent) |
NA |
1.0 (referent) |
NA |
|
Age, y | ||||||
<36 | 25/58 (43.1) | 1.03 (0.59–1.80) | 0.9285 | NA | NA | |
>36 |
24/56 (42.9) |
1.0 (referent) |
NA |
NA |
NA |
|
Previous TB treatment‡ | ||||||
Yes | 38/92 (41.3) | 1.47 (0.53–4.13) | 0.4614 | 1.28 (0.45–3.65) | 0.6391 | |
No | 4/15 (26.7) | 1.0 (referent) | NA | 1.0 (referent) | NA | |
Unknown |
7/7 (100) |
NA |
NA |
NA |
NA |
|
Initial sputum smear result | ||||||
Positive | 30/67 (44.8) | 1.05 (0.59–1.86) | 0.8704 | NA | NA | |
Negative |
19/47 (40.4) |
1.0 (referent) |
NA |
NA |
NA |
|
HIV status‡ | ||||||
Positive | 36/82 (43.9) | 1.14 (0.58–2.25) | 0.6971 | 1.30 (0.61–2.78) | 0.4966 | |
Negative | 11/25 (44.0) | 1.0 (referent) | NA | 1.0 (referent) | ||
Unknown |
2/7 (28.6) |
NA |
NA |
NA |
NA |
|
Adverse event | ||||||
Yes | 23/52 (44.2) | 1.02 (0.58–1.79) | 0.9420 | NA | NA | |
No | 26/62 (41.9) | 1.0 (referent) | NA | NA | NA |
*XDR TB, extensively drug-resistant tuberculosis; NA, not applicable.
†Significant variables or variables that caused >10% change in the bivariate hazard ratio were included in the multivariate model.
‡Patients whose HIV status or previous TB treatment history was unknown were excluded from analyses.
Page created: March 21, 2013
Page updated: March 21, 2013
Page reviewed: March 21, 2013
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