Volume 19, Number 3—March 2013
Dispatch
Lymphogranuloma Venereum in Men Screened for Pharyngeal and Rectal Infection, Germany
, Sandra Dudareva-Vizule, Hilmar Wisplinghoff, Fabian Wisplinghoff, Andrea Sailer, Klaus Jansen, Birgit Henrich, and Ulrich Marcus
Table 2
Characteristics of MSM patients with CT infection, by LGV status, Germany, 2009–2010*
| Characteristic | LGV positive, n = 19 | LGV negative, n = 95 | p value | OR (95%CI) |
|---|---|---|---|---|
|
Median age, y (range)
|
37 (27–55)
|
30 (19–67)
|
0.004
|
|
| Origin | n = 16 | n = 80 | ||
|
Germany, % (no.) |
87.5 (14)
|
80.0 (64)
|
0.73†
|
1.75 (0.34–17.33)
|
| Reported symptoms | n = 15 | n = 69 | ||
|
None, % (no.) |
53.3 (8)‡
|
73.9 (51)
|
0.13
|
2.48 (0.79–7.81)
|
| Median no. male sex partners in past 6 mo (range) | ||||
|
All partners |
9 (1–1,000) | 5 (1–150) | 0.11 | |
|
Unprotected anal sex partners |
1.5 (0–80)
|
1 (0–150)
|
0.43
|
|
| Meeting place for >1 of last 3 partners, % | n = 16 | n = 82 | ||
|
The Internet |
62.5 | 65.9 | 0.80 | 0.86 (0.29–2.62) |
|
Bar/pub/club |
50.0 | 26.8 | 0.08† | 2.73 (0.91–8.15) |
|
Sauna |
6.3 | 13.4 | 0.68† | 0.43 (0.01–3.43) |
|
Sex party |
18.8 | 3.7 | 0.05† | 6.08 (0.71–49.10) |
|
Pornography cinema |
0 | 7.3 | 0.59† | 0.60 (0.00–4.47) |
|
Cruising |
0 | 4.9 | 1.0† | 0.95 (0.00–8.02) |
|
At friends’ homes |
12.5 | 11.0 | 1.0† | 1.16 (0.11–6.52) |
|
Other |
6.3
|
7.3
|
1.0†
|
0.84 (0.02–7.81)
|
| Location of sexual contact with last 3 partners, %§ | 15 patients/33 answers | 57 patients/144 answers | ||
|
Germany |
100.0 | 95.1 | 0.33 | 2.18 (0.29–∞) |
|
Abroad |
0
|
4.9
|
|
|
| HIV status | ||||
|
% Positive |
57.9 | 41.1 | 0.18 | 1.97 (0.73–5.36) |
|
If positive |
||||
|
Median time since diagnosis, y (range) |
4.5 (2.75–13.67) | 2.1 (0–20.25) | 0.22 | |
|
HIV therapy, % |
n = 8 | n = 25 | ||
|
Combination therapy |
87.5 | 52.0 | 0.11† | 6.46 (0.63–312.96) |
|
No therapy |
12.5 | 48.0 | ||
|
Viral load, copies/mL, % |
n = 8 | n = 22 | ||
|
Undetectable or <1,000 |
100.0 | 54.5 | 0.03† | 0.12 (0.00–0.94) |
|
>1,000 |
0
|
45.5
|
|
|
|
History of CT testing and past infections
|
19
|
95
|
|
|
| CT test ever, yes/no | 9/4 | 27/26 | 0.35† | 2.17 (0.52–10.73) |
|
If yes, when |
||||
|
Past 3 mo |
6 | 11 | ||
|
Past 6 mo |
1 | 3 | ||
|
Past 12 mo |
2
|
5
|
|
|
| History of CT infection | n = 16 | n = 82 | ||
|
Yes, % (no.) |
43.8 (7) | 12.2 (10) | 0.01† | 5.60 (1.40–21.24) |
|
If yes, when |
||||
|
Past month |
4¶ | 2 | 0.57† | 3.0 (0.26–35.33) |
|
>1 mo |
2
|
3
|
|
|
| If history of CT infection in past month, type of current CT infection, no. | ||||
|
Anorectal |
4 | 1 | ||
|
Urethral |
0 | 1 | ||
*No. indicates no. persons. MSM, men who have sex with men; CT, Chlamydia trachomatis; LGV, lymphogranuloma venereum; OR, odds ratio.
†Exact logistic regression
‡3 of these patients were from 1 proctological referral practice
§Multiple answers possible.
¶Of 2 pharyngeal LGV cases, the HIV-positive patient was asymptomatic and the HIV-negative patient reported night-sweats.