Volume 19, Number 4—April 2013
CME ACTIVITY - Research
Serotype IV and Invasive Group B Streptococcus Disease in Neonates, Minnesota, USA, 2000–20101
Table 5
Molecular characteristics of serotype IV GBS isolates causing invasive disease in infants and adults, Minnesota*
Isolate source† | PFGE profile† | Allelic profile‡ | Sequence type§ | Clonal complex¶ |
---|---|---|---|---|
Mother, early-onset | 38d | 1,1,3,1,1,12,2 | 196 | 1 |
Infant, early-onset | 40 | 1,1,3,1,1,12,2 | 196 | 1 |
Nonpregnant adult | 39a | 1,1,3,1,41,12,2 | 459 | 1 |
Mother, early-onset | 36c | 2,25,1,2,1,1,1 | 291 | 17 |
Nonpregnant adult | 36d | 2,25,1,2,1,1,1 | 291 | 17 |
Infant, late-onset | 37 | 5,25,4,3,2,3,3 | 452 | 23 |
Infant, late-onset | 37a | 5,25,4,3,2,3,3 | 452 | 23 |
Infant, early-onset | 37a | 5,25,4,3,2,3,1 | 468 | 23 |
*GBS, group B Streptococcus; PFGE, pulsed-field gel electrophoresis.
†Early-onset, patient age birth–6 days or mother during peripartum period; late-onset, patient age 7–180 days.
‡Multilocus sequence type of 7 housekeeping genes (adhP, pheS, atr, glnA, sdhA, glcK, tkt).
§From http://pubmlst.org/sagalactiae database.
¶Determined by eBurst analysis (25).
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1This work was presented in part at the XVIII Lancefield International Symposium on Streptococci and Streptococcal Diseases, September 4–8, 2011, Palermo, Italy.