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Volume 19, Number 4—April 2013
CME ACTIVITY - Research

Serotype IV and Invasive Group B Streptococcus Disease in Neonates, Minnesota, USA, 2000–20101

Patricia FerrieriComments to Author , Ruth Lynfield, Roberta Creti, and Aurea E. Flores
Author affiliations: University of Minnesota Medical School, Minneapolis, Minnesota, USA (P. Ferrieri, A.E. Flores); Minnesota Department of Health, St. Paul, Minnesota, USA (R. Lynfield); Istituto Superiore di Sanità, Rome, Italy (R. Creti)

Main Article

Table 5

Molecular characteristics of serotype IV GBS isolates causing invasive disease in infants and adults, Minnesota*

Isolate source† PFGE profile† Allelic profile‡ Sequence type§ Clonal complex¶
Mother, early-onset 38d 1,1,3,1,1,12,2 196 1
Infant, early-onset 40 1,1,3,1,1,12,2 196 1
Nonpregnant adult 39a 1,1,3,1,41,12,2 459 1
Mother, early-onset 36c 2,25,1,2,1,1,1 291 17
Nonpregnant adult 36d 2,25,1,2,1,1,1 291 17
Infant, late-onset 37 5,25,4,3,2,3,3 452 23
Infant, late-onset 37a 5,25,4,3,2,3,3 452 23
Infant, early-onset 37a 5,25,4,3,2,3,1 468 23

*GBS, group B Streptococcus; PFGE, pulsed-field gel electrophoresis.
†Early-onset, patient age birth–6 days or mother during peripartum period; late-onset, patient age 7–180 days.
‡Multilocus sequence type of 7 housekeeping genes (adhP, pheS, atr, glnA, sdhA, glcK, tkt).
§From http://pubmlst.org/sagalactiae database.
¶Determined by eBurst analysis (25).

Main Article

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Main Article

1This work was presented in part at the XVIII Lancefield International Symposium on Streptococci and Streptococcal Diseases, September 4–8, 2011, Palermo, Italy.

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