Volume 19, Number 5—May 2013
Research
Changes in Severity of Influenza A(H1N1)pdm09 Infection from Pandemic to First Postpandemic Season, Germany
Table 1
Demographic and clinical characteristics of influenza infected patients stratified by season, 2009–10 and 2010–11, University Hospital Heidelberg, Germany*
| Characteristic | No. (%) patients |
p value | |
|---|---|---|---|
| 2009–10 | 2009–10 | ||
| Total no. admitted patients | 102 | 76 | |
| Male sex | 56 (55) | 36 (47) | 0.32 |
| Age, mean | 18.2 | 38 | <0.05 |
| Days in hospital | 7.6 | 13.9 | <0.05 |
| Admitted to ICU | 14 (14) | 35 (46) | <0.05 |
| Severely diseased | 15 (15) | 35 (46) | <0.05 |
| Died | 5 (5) | 9 (12) | 0.05 |
| Pregnant | 4 (4) | 5 (7) | 0.50 |
| Pneumonia | 29 (28) | 33 (43) | <0.05 |
| Mechanical ventilation | 11 (11) | 24 (32) | <0.05 |
| Underlying medical condition | 52 (51) | 57 (75) | <0.05 |
| Immunosuppression | 22 (22) | 41 (54) | <0.05 |
| Cancer | 2 (2) | 4 (5) | 0.23 |
| Blood malignancy | 10 (10) | 15 (20) | 0.06 |
| Solid organ transplant | 7 (7) | 14 (18) | <0.05 |
| Autoimmune | 5 (5) | 6 (8) | 0.41 |
| Other | 2 (2) | 3 (4) | 0.65 |
| Chronic lung disease | 9 (9) | 13 (17) | 0.10 |
| Cardiovascular disease | 25 (25) | 33 (43) | <0.05 |
| Renal impairment | 9 (9) | 20 (26) | <0.05 |
| Diabetes | 6 (6) | 11 (14) | 0.05 |
| Metabolic dysfunction | 15 (15) | 13 (17) | 0.66 |
| Neurologic impairment | 15 (15) | 8 (11) | 0.41 |
| CRP level on admission, mg/L† | 34.7 (range <2.0–213.6) | 69.2 (range <2.0–381.4) | <0.05 |
| Leukocyte count on admission, /nL† | 9.9 [range 0.1–108.7) | 9.1 (range 0.9–48.8) | |
*ICU, intensive care unit; CRP; C-reactive protein.
†Or the following day if not tested on admission.
1These authors contributed equally to this article.
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Page updated: April 23, 2013
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