Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 20, Number 1—January 2014

Novel Avian Coronavirus and Fulminating Disease in Guinea Fowl, France

Etienne Liais1, Guillaume Croville1, Jérôme Mariette, Maxence Delverdier, Marie-Noëlle Lucas, Christophe Klopp, Jérôme Lluch, Cécile Donnadieu, James S. Guy, Léni Corrand, Mariette F. Ducatez, and Jean-Luc GuérinComments to Author 
Author affiliations: French National Institute for Agricultural Research (INRA), Toulouse, France (E. Liais, G. Croville, M. Delverdier, M.-N. Lucas, L. Corrand, M.F. Ducatez, J.-L. Guérin); Ecole Nationale Vétérinaire, Toulouse (E. Liais, G. Croville, M. Delverdier, M.-N. Lucas, L. Corrand, M.F. Ducatez, J.-L. Guérin); INRA 31326, Castanet-Tolosan, France (J. Mariette, C. Klopp; J. Lluch, C. Donnadieu); North Carolina State University, Raleigh, North Carolina, USA (J. Guy)

Main Article

Table 1

Distribution of reads generated by sequencing of pooled intestinal contents from guinea fowl poults with fulminating disease France, 2010–2011*

Read type No. (%) reads
Total reads generated 476,430
Cellular reads 142,739 (30)
Bacterial reads 246,787 (51.8)
Archaea reads 35,271 (7.4)
Phage, plant, and insect virus reads 32,477 (6.8)
Eukaryote virus reads 19,155 (4.0)
Coronavirus reads 1,441 (7.5)†

*Sequencing was performed by using MiSeq (Illumina, San Diego, CA, USA) and analyzed by using the GAAS ( algorithm with an expected value of 10−3 (7).
†Percent within eukaryote virus reads.

Main Article

  1. Brahem  A, Demarquez  N, Beyrie  M, Vuillaume  A, Fleury  HJ. A highly virulent togavirus-like agent associated with the fulminating disease of guinea fowl. Avian Dis. 1992;36:1438 . DOIPubMedGoogle Scholar
  2. Andral  B, Lagadic  M, Louzis  C, Guillou  JP, Gourreau  JM. Fulminating disease in guinea fowl: etiological investigation. Point Veterinaire. 1987;19:51520.
  3. Toffan  A, Catania  S, Salviato  A, De Battisti  C, Vascellari  M, Toson  M, Experimental infection of poults and guinea fowl with genetically distinct avian astroviruses. Avian Pathol. 2012;41:42935. DOIPubMedGoogle Scholar
  4. van Boheemen  S, de Graaf  M, Lauber  C, Bestebroer  TM, Raj  VS, Zaki  AM, Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans. MBio. 2012;3:e0047312. DOIPubMedGoogle Scholar
  5. Gouilh  MA, Puechmaille  SJ, Gonzalez  J-P, Teeling  E, Kittayapong  P, Manuguerra  J-C. SARS-coronavirus ancestor’s foot-prints in South-East Asian bat colonies and the refuge theory. Infect Genet Evol. 2011;11:1690702. DOIPubMedGoogle Scholar
  6. Victoria  JG, Kapoor  A, Li  L, Blinkova  O, Slikas  B, Wang  C, Metagenomic analyses of viruses in stool samples from children with acute flaccid paralysis. J Virol. 2009;83:464251. DOIPubMedGoogle Scholar
  7. Angly  FE, Willner  D, Prieto-Davó  A, Edwards  RA, Schmieder  R, Vega-Thurber  R, The GAAS metagenomic tool and its estimations of viral and microbial average genome size in four major biomes. PLOS Comput Biol. 2009;5:e1000593. DOIPubMedGoogle Scholar
  8. Stephensen  CB, Casebolt  DB, Gangopadhyay  NN. Phylogenetic analysis of a highly conserved region of the polymerase gene from 11 coronaviruses and development of a consensus polymerase chain reaction assay. Virus Res. 1999;60:1819. DOIPubMedGoogle Scholar
  9. Breslin  JJ, Smith  LG, Barnes  HJ, Guy  JS. Comparison of virus isolation, immunohistochemistry, and reverse transcriptase–polymerase chain reaction procedures for detection of turkey coronavirus. Avian Dis. 2000;44:62431. DOIPubMedGoogle Scholar
  10. Jackwood  MW, Hall  D, Handel  A. Molecular evolution and emergence of avian gammacoronaviruses. Infect Genet Evol. 2012;12:130511. DOIPubMedGoogle Scholar
  11. Maurel  S, Toquin  D, Briand  FX, Queguiner  M, Allee  C, Bertin  J, First full-length sequences of the S gene of European isolates reveal further diversity among turkey coronaviruses. Avian Pathol. 2011;40:17989. DOIPubMedGoogle Scholar
  12. Cavanagh  D. Coronaviruses in poultry and other birds. Avian Pathol. 2005;34:43948. DOIPubMedGoogle Scholar
  13. Woo  PCY, Lau  SKP, Lam  CSF, Lau  CCY, Tsang  AKL, Lau  JHN, Discovery of seven novel mammalian and avian coronaviruses in the genus Deltacoronavirus supports bat coronaviruses as the gene source of Alphacoronavirus and Betacoronavirus and avian coronaviruses as the gene source of Gammacoronavirus and Deltacoronavirus. J Virol. 2012;86:39954008. DOIPubMedGoogle Scholar
  14. Jackwood  MW, Boynton  TO, Hilt  DA, McKinley  ET, Kissinger  JC, Paterson  AH, Emergence of a group 3 coronavirus through recombination. Virology. 2010;398:98108. DOIPubMedGoogle Scholar
  15. Circella  E, Camarda  A, Martella  V, Bruni  G, Lavazza  A, Buonavoglia  C. Coronavirus associated with an enteric syndrome on a quail farm. Avian Pathol. 2007;36:2518. DOIPubMedGoogle Scholar

Main Article

1These authors contributed equally to this article.

Page created: January 03, 2014
Page updated: January 03, 2014
Page reviewed: January 03, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.