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Volume 20, Number 12—December 2014
Dispatch

Human Hantavirus Infections in the Netherlands

Jussi SaneComments to Author , Johan Reimerink, Margriet Harms, Jacinta Bakker, Lapo Mughini-Gras, Barbara Schimmer, and Wilfrid van Pelt
Author affiliations: National Institute for Public Health and the Environment, Bilthoven, the Netherlands (J. Sane, J. Reimerink, M. Harms, J. Bakker, L. Mughini-Gras, B. Schimmer, W. van Pelt); European Centre for Disease Prevention and Control, Stockholm, Sweden (J. Sane)

Main Article

Table

Selected factors associated with positivity for IgG against Puumala virus, the Netherlands, December 2008–December 2013*

Factor No. persons IFA positive/no. tested (%) Single variable
Multivariable
aOR (95% CI)† p value aOR (95% CI)‡ p value
Sex
M 9/1,368 (0.66) Reference Reference NA
F
18/1,565 (1.15)
1.79 (0.89–3.57)
0.10

1.87 (0.97–3.61)
0.06
Age, y
0–15 7/824 (0.84) Reference Reference NA
16–40 7/822 (0.85) 1.03 (0.36–2.93) 0.96 1.0 (0.33–3.07) 0.99
41–60 5/585 (0.85) 0.91 (0.26–3.19) 0.88 0.86 (0.22–3.32) 0.82
>60
8/702 (1.14)
1.32 (0.48–3.62)
0.59

1.69 (0.51–5.56)
0.39
Owning ≥1 dog
No 12/2147 (0.56) Reference Reference NA
Yes
15/786 (1.53)
4.51 (1.81–11.30)
0.001

3.49 (1.50–8.14)
0.004
Owning any livestock§
No 19/2,706 (0.70) Reference Reference NA
Yes
8/227 (3.52)
6.97 (2.45–19.82)
<0.001

4.79 (1.69–13.57)
0.003
Net monthly income, Euros
<1,150 11/426 (2.58) Reference NA NA
1,151–3,050 9/1,539 (5.84) 0.27 (0.05–1.47) 0.13 NA NA
>3,501
1/242 (0.41)
0.21 (0.03–1.79)
0.15

NA
NA
Occupational exposure to any animal
No 25/2794 (0.89) Reference NA NA
Yes 2/139 (1.43) 1.72 (0.25–11.77) 0.58 NA NA

*IFA, indirect immunofluorescence assay; aOR, adjusted odds ratio; NA, not applicable. The municipality-level random effect was significant (p = 0.001, by log-likelihood ratio test).
†Adjusted for age, sex, and clustering at municipality level (random effect).
‡Adjusted for age, sex, clustering at municipality level (random effect), and the other covariates included in the multivariable model.
§Cattle, pigs, sheep, goats, poultry, and other livestock.

Main Article

Page created: November 19, 2014
Page updated: November 19, 2014
Page reviewed: November 19, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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