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Volume 20, Number 3—March 2014
CME ACTIVITY - Research

Use of Drug-Susceptibility Testing for Management of Drug-Resistant Tuberculosis, Thailand, 2004–2008

Eugene Lam, Sriprapa Nateniyom, Sara Whitehead, Amornrat Anuwatnonthakate, Patama Monkongdee, Apiratee Kanphukiew, Jiraphan Inyaphong, Wanlaya Sitti, Navarat Chiengsorn, Saiyud Moolphate, Suporn Kavinum, Narin Suriyon, Pranom Limsomboon, Junya Danyutapolchai, Chalinthorn Sinthuwattanawibool, and Laura Jean PodewilsComments to Author 
Author affiliations: US Centers for Disease Control and Prevention (US CDC), Atlanta, Georgia, USA (E. Lam, S. Whitehead, L.J. Podewils); Thailand Ministry of Public Health (MOPH), Nonthaburi, Thailand (S. Nateniyom); Thailand MOPH–US CDC, Nonthaburi (S. Whitehead, A. Anuwatnonthakate, P. Monkongdee, A. Kanphukiew, J. Danyutapolchai, C. Sinthuwattanawibool); Office of Disease Prevention and Control 7, Ubon-ratchathani, Thailand (J. Inyaphong, W. Sitti); Bangkok Metropolitan Health Administration, Bangkok Thailand (N. Chiengsorn); Research Institute of Tuberculosis (RIT-Japan), Tokyo, Japan (S. Moolphate); Tak Provincial Public Health Office, Tak, Thailand (S. Kavinum); Chiang Rai Provincial Public Health Office, Chiang Rai, Thailand (N. Suriyon); Phuket Provincial Public Health Office, Phuket, Thailand (P. Limsomboon)

Main Article

Table 1

Baseline demographic characteristics for patients with drug-resistant TB, Thailand, 2004–2008*

Characteristic Patients with RIF-resistant TB, n = 121
 Patients with MDR TB, n = 369
 Patients with RIF-resistant vs. MDR TB, p value‡
Included, n = 36 Excluded, n = 85 P value† Included, n = 172 Excluded, n = 197 P value†
Age, median (IQR), y 42 (34–58) 36 (29–48) 0.02 39 (29–50) 36 (28–47) 0.11 0.10
Sex
M 22 (61.1) 55 (64.7) 0.71 117 (68.0) 128 (65.0) 0.58 0.42
F 14 (38.9) 30 (35.3) 55 (32.0) 68 (34.5)
Data missing
 0 (0.0)
 0 (0.0)
0 (0.0)
 1 (0.5)
Marital status
Married 22 (61.1) 39 (46.4) 0.32 93 (54.1) 85 (43.1) 0.001 0.06
Single/divorced/widowed 13 (36.1) 43 (51.2) 79 (45.9) 98 (50.0)
Data missing
 1 (2.8)
 2 (2.4)
0 (0.0)
 13 (6.6)
Nationality
Thai 33 (91.7) 76 (89.4) 0.70 144 (83.7) 170 (86.3) 0.49 0.22
Not Thai 3 (8.3) 9 (10.6) 28 (16.3) 27 (13.7)

*Patients were from the Thailand TB Active Surveillance Network and were either included or not included in the current study. Data are no. (%) unless otherwise indicated. TB, tuberculosis; RIF, rifampin; MDR, multidrug-resistance; IQR, interquartile range.
†p values reflect comparison between included and excluded patients in each TB drug resistance group.
‡p values reflect comparison between included RIF-resistant patients and MDR TB patients.

Main Article

Page created: February 25, 2014
Page updated: February 25, 2014
Page reviewed: February 25, 2014
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