Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 20, Number 7—July 2014

Epidemiology, Clinical Manifestations, and Outcomes of Streptococcus suis Infection in Humans

Vu Thi Lan Huong1, Ngo Ha1, Nguyen Tien Huy1, Peter Horby, Ho Dang Trung Nghia, Vu Dinh Thiem, Xiaotong Zhu, Ngo Thi Hoa, Tran Tinh Hien, Javier Zamora, Constance Schultsz, Heiman Frank Louis Wertheim, and Kenji HirayamaComments to Author 
Author affiliations: Oxford University Clinical Research Unit, Hanoi, Vietnam (V.T.L. Huong, P. Horby, H.F.L. Wertheim); University of Oxford, Oxford, UK (V.T.L. Huong, P. Horby, H.F.L. Wertheim, N.T. Hoa); Nagasaki University, Nagasaki, Japan (N. Ha, N.T. Huy, X. Zhu, K. Hirayama); Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam (H.D.T. Nghia, N.T. Hoa, T.T. Hien, C. Schultsz); National Institute of Hygiene and Epidemiology, Hanoi (V.D. Thiem); Ramón y Cajal Hospital, Madrid, Spain (J. Zamora); CIBER Epidemiologia y Salud Publica, Madrid (J. Zamora); Pham Ngoc Thach University of Medicine, Ho Chi Minh City (H.D.T. Nghia); University of Amsterdam, Amsterdam, the Netherlands (C. Schultsz)

Main Article

Table 2

Epidemiologic factors of patients with Streptococcus suis infection included in a systematic review

Variable Single-case dataset, %* Large studies, median
(range), % Meta-analysis, pooled mean (95% CI), %† No. studies meta-analyzed, %‡
Mean age, y, n = 156 49.4 50.5 (37.0–61.2) 51.4 (49.5–53.2) 25
Male sex, n = 155 83.2 77.5 (37.5–100) 76.6 (72.2–80.6) 26
Pig-related occupation 58.6 25.0 (0–100) 38.1 (24.4–53.9) 21
Contact with pig/pork 15.5 33.3 (2.4–100) 33.9 (21.1–49.5) 14
Eating of high-risk food 4.0 53.3 (5.9–88.7) 37.3 (20.2–58.3) 9
Skin injury 19.5 16.0 (9.5–71.4) 25.1 (15.1–38.7) 8
Drinking of alcohol 8.6 23.0 (4.8–83.9) 29.7 (17.2–46.3) 13
Concurrent diabetes§ 2.9 7.2 (3.2–25.0) 8.0 (4.6–13.7) 9

*N = 174 unless otherwise indicated.
†Random-effects model unless otherwise specified.
‡Include the single-case dataset and the large studies (Technical Appendix Table 2).
§Other less common underlying conditions are listed in Technical Appendix Table 3.

Main Article

1These authors contributed equally to this article.

Page created: June 17, 2014
Page updated: June 17, 2014
Page reviewed: June 17, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.