Volume 20, Number 7—July 2014
Letter
Candida auris–Associated Candidemia, South Africa
Table
Identification and antifungal susceptibility results of 4 Candida auris isolates from 4 male patients with candidemia, South Africa, October 2012–October 2013*
Isolate ID | Patient age, y | Hospital unit | Vitek-2 YST† | API 20C AUX† | DNA sequence analysis‡ | MIC |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AMB | FLX | VRC | POS | ITC | 5FC | CAS | MFG | AFG | ||||||
208 | 85 | High-care | C. haemulonii | Rhodotorula glutinis | C. auris | 1 | >256 | 0.5 | 0.03 | 0.12 | 0.12 | 0.25 | 0.06 | 0.25 |
209 | 60 | Medical ICU | C. haemulonii | R. glutinis | C. auris | 0.5 | >256 | 1 | 0.06 | 0.12 | 0.12 | 0.12 | 0.06 | 0.12 |
224 | 73 | Burn | C. haemulonii | R. glutinis | C. auris | 1 | >256 | 2 | 0.06 | 0.25 | 0.12 | 0.25 | 0.12 | 0.25 |
293 | 27 | Trauma ICU | C. haemulonii | R. glutinis | C. auris | 1 | 64 | 0.25 | 0.015 | 0.06 | 0.06 | 0.03 | 0.06 | 0.06 |
*AMB, amphotericin B; FLX, fluconazole; VRC, voriconazole; POS, posaconazole; ITC, itraconazole; 5FC, flucytosine; CAS, caspofungin; MFG, micafungin; AFG, anidulafungin.
†bioMérieux, Marcy ľEtoile, France.
‡Sequence data for the 4 isolates have been deposited in GenBank, accession nos. KJ1236762–KJ126765 and KJ126758–KJ126761 for the internal transcribed spacer and D1/D2 regions, respectively.