Independent Origin of Plasmodium falciparum Antifolate Super-Resistance, Uganda, Tanzania, and Ethiopia
Michael Alifrangis
1, Sidsel Nag
1
, Mette L. Schousboe, Deus S. Ishengoma, John Lusingu, Hirva Pota, Reginald A. Kavishe, Richard Pearce, Rosalynn Ord, Caroline Lynch, Seyoum Dejene, Jonathan Cox, John Rwakimari, Daniel T.R. Minja, Martha M. Lemnge, and Cally Roper
Author affiliations: Centre for Medical Parasitology at Department of International Health, Immunology, and Microbiology, Faculty of Health and Medical Science, University of Copenhagen and at Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet),; Copenhagen, Denmark (M. Alifrangis, S. Nag, M.L. Schousboe); Tanga Research Centre, Tanzania (D. Ishengoma, J. Lusingu, D.T.R. Minja, M.M. Lemnge); London School of Hygiene and Tropical Medicine, London, UK (H. Pota, R. Pearce, R. Ord, C. Lynch, J. Cox, C. Roper); Kilimanjaro Christian Medical University College, Moshi, Tanzania (R.A. Kavishe); Kilimanjaro Clinical Research Institute, Moshi (R.A. Kavishe); Médécins Sans Frontières, Humera, Ethiopia (S. Dejene); Ministry of Health of Uganda, Kampala, Uganda (J. Rwakimari)
Main Article
Table
Study sites and number of samples genotyped for super-resistant Plasmodium falciparum, eastern Africa
Study site. |
SGEAA
|
|
SGEGA
|
Total haplotype diversity |
No. samples |
Haplotype diversity |
|
No. samples |
Haplotype diversity |
Ethiopia, Humera, Tigray |
35 |
4 |
|
41 |
1 |
4 |
Uganda |
|
|
|
|
|
|
Bufundi, Kabale |
24 |
5 |
|
14 |
3 |
7 |
Kebisoni, Rukungiri |
27 |
5 |
|
14 |
3 |
7 |
Tanzania |
|
|
|
|
|
|
Hale, Tanga |
21 |
6 |
|
15 |
3 |
8 |
Korogwe, Tanga |
64 |
21 |
|
19 |
3 |
22 |
Magoda, Tanga |
7 |
3 |
|
15 |
6 |
6 |
Main Article
Page created: July 18, 2014
Page updated: July 18, 2014
Page reviewed: July 18, 2014
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