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Volume 20, Number 9—September 2014

CME ACTIVITY - Research

Pneumocystis jirovecii Pneumonia in Patients with or without AIDS, France

Antoine Roux, Emmanuel Canet, Sandrine Valade, Florence Gangneux-Robert, Samia Hamane, Ariane Lafabrie, Daniéle Maubon, Anne Debourgogne, Soléne Le Gal, Fréderic Dalle, Marion Leterrier, Dominique Toubas, Christelle Pomares, Anne Pauline Bellanger, Julie Bonhomme, Antoine Berry, Isabelle Durand-Joly, Denis Magne, Denis Pons, Christophe Hennequin, Eric Maury, Patricia Roux1, and Élie AzoulayComments to Author 
Author affiliations: Centre Medico-Chirurgical FOCH, Suresnes, France (A. Roux); Hôpital Saint-Louis, Paris, France (E. Canet, S. Valade, S. Hamane, A. Lafabrie, É. Azoulay); Centre Hospitalier Universitaire (CHU) de Rennes, Rennes, France (F. Gangneux-Robert ); CHU de Grenoble, Grenoble, France (D. Maubon); CHU de Nancy, Nancy, France (A. Debourgogne); Centre Hospitalier Régional et Universitaire de Brest, Brest, France (S. Le Gal); CHU de Dijon, Dijon, France (F. Dalle); CHU de Nantes, Nantes, France (M. Leterrier); CHU de Reims, Reims, France (D. Toubas); Hôpital de l’Archet, Nice, France (C. Pomares); CHU Jean Minjoz, Besançon, France (A.P. Bellanger); CHU Côte de Nacre, Caen, France (J. Bonhomme); CHU de Toulouse, Toulouse, France (A. Berry); CHU de Lille, Lille, France (I. Durand-Joly); Hôpital Saint-Antoine, Paris (D. Magne, C. Hennequin, P. Roux, E. Maury); CHU Gabriel Montpied, Clermont-Ferrand, France (D. Pons)

Main Article

Table 2

Clinical management of 544 AIDS and non-AIDS patients after diagnosis with PCP, France, January 1, 2007–December 31, 2010*

Characteristic
AIDS patients, n = 223
Non-AIDS patients, n = 321
p value
Days from admission to treatment initiation, median (IQR) 1 (0–2) 2 (0–6) <0.0001
Intensive care admission 65 (35) 134 (50) 0.0015
Immediate oxygen needed 87 (49) 160 (69) <0.0001
Oxygen flow rate, L/min, mean (95% CI)
2 (1.3–2.8)
3.8 (2.8–4.8)
0.015
Mechanical ventilation
Noninvasive needed 17 (8) 50 (16) 0.0053
Noninvasive failed 16 (8) 46 (15) 0.013
Invasive needed
25 (11.0)
98 (30.5)
<0.0001
Hospital deaths 8 (4) 75 (27) <0.0001

*Values are no. (%) patients except as indicated. PCP, Pneumocystis jirovecii pneumonia; IQR, interquartile range.

Main Article

1Deceased.

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