Volume 21, Number 1—January 2015
Dispatch
Antibodies against Borrelia burgdorferi sensu lato among Adults, Germany, 2008–2011
, Volker Fingerle, Christiane Klier, Michael Thamm, and Klaus Stark
Table
Stratified seroprevalence of Borrelia burgdorferi sensu lato IgG detected by combined ELISA and line blot testing in adults and results of weighted logistic regression analysis of potential risk factors for seropositivity, Germany, 2008–2011*
| Characteristic† | No. positive/no. total† | Prevalence (95% CI) | Univariable analysis |
Multivariable analysis |
|||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | ||||
| Sex | |||||||
| F | 240/3,614 | 5.8 (4.9–6.7) | Ref | Ref | Ref | Ref | |
| M |
501/3,331 |
13.0 (11.4–14.8) |
2.44 (2.01–2.96) |
<0.001 |
2.61 (2.15–3.16) |
<0.001 |
|
| Age group, y | |||||||
| 18–29 | 62/1,043 | 6.0 (4.5–8.0) | Ref | Ref | Ref | Ref | |
| 30–39 | 50/829 | 6.3 (4.4–9.0) | 1.05 (0.64–1.69) | 0.854 | 1.07 (0.67–1.72) | 0.779 | |
| 40–49 | 83/1,263 | 6.4 (5.0–8.2) | 1.07 (0.72–1.58) | 0.737 | 1.04 (0.69–1.55) | 0.856 | |
| 50–59 | 126/1,373 | 8.5 (6.8–10.7) | 1.46 (1.01–2.10) | 0.043 | 1.39 (0.97–1.99) | 0.069 | |
| 60–69 | 186/1,361 | 13.2 (10.9–15.9) | 2.37 (1.65–3.40) | <0.001 | 2.37 (1.65–3.45) | <0.001 | |
| 70–79 |
234/1,076 |
20.0 (16.9–23.6) |
3.91 (2.77–5.51) |
<0.001 |
4.02 (2.84–5.70) |
<0.001 |
|
| Residence location | |||||||
| West‡ | 484/4.748 | 9.1 (8.0–10.4) | Ref | Ref | – | – | |
| East§ | 257/2,197 | 10.4 (8.5–12.6) | 1.15 (0.89–1.49) | 0.273 | – | – | |
| North¶ | 181/1,767 | 9.0 (7.2–11.0) | 1.11 (0.82–1.51) | 0.479 | 1.16 (0.86–1.57) | 0.318 | |
| Middle# | 304/3,087 | 8.1 (6.7–9.8) | Ref | Ref | Ref | Ref | |
| South** |
256/2,091 |
11.2 (9.4–13.3) |
1.43 (1.08–1.88) |
0.011 |
1.34 (1.03–1.75) |
0.032 |
|
| Population of residence municipality | |||||||
| <5,000 | 189/1,258 | 15.4 (12.8–18.4) | 2.50 (1.85–3.30) | <0.001 | 2.13 (1.54–2.97) | <0.001 | |
| 5,000 to <20,000 | 185/1,685 | 10.0 (8.0–12.5) | 1.51 (1.11–2.07) | 0.010 | 1.33 (0.96–1.84) | 0.082 | |
| 20,000 to <100,000 | 193/2,030 | 8.4 (6.9–10.2) | 1.24 (0.92–1.66) | 0.154 | 1.21 (0.88–1.67) | 0.231 | |
| >100,000 |
174/1,972 |
6.9 (5.6–8.4) |
Ref |
Ref |
Ref |
Ref |
|
| Foreign national†† | |||||||
| No | 721/6,528 | 10.0 (8.9–11.2) | Ref | Ref | Ref | Ref | |
| Yes |
18/396 |
4.3 (2.5–7.5) |
0.41 (0.22–0.75) |
0.004 |
0.54 (0.30–0.90) |
0.041 |
|
| Pet in household | |||||||
| None | 502/4,596 | 9.5 (8.4–10.7) | Ref | Ref | – | – | |
| Any | 217/2,182 | 9.3 (7.8–11.0) | 0.98 (0.80–1.20) | 0.834 | – | – | |
| Dog | |||||||
| No | 639/5,909 | 9.4 (8.4–10.6) | Ref | Ref | – | – | |
| Yes | 80/858 | 9.3 (7.0–12.2) | 0.98 (0.71–1.35) | 0.909 | – | – | |
| Cat | |||||||
| No | 622/5,886 | 9.2 (8.2–10.3) | Ref | Ref | – | – | |
| Yes | 119/1,077 | 10.3 (8.1–13.0) | 1.13 (0.87–1.47) | 0.356 | – | – | |
| Other animals | |||||||
| No | 655/ 6,001 | 9.7 (8.8–10.6) | Ref | Ref | – | – | |
| Yes |
64/766 |
7.7 (5.8–10.1) |
0.78 (0.56–1.07) |
0.127 |
– |
– |
|
| Total | 741/6,945 | 9.4 (8.4–10.0) | – | – | – | – | |
*OR, odds ratio; Ref, reference; –, not included in the final model.
†Unweighted.
‡Western states: Baden-Württemberg, Bavaria, Bremen, Hamburg, Hesse, Lower Saxony, Northrhine-Westfalia, Rhineland-Palatinate, Saarland, Schleswig-Holstein.
§Eastern states: Berlin, Brandenburg, Mecklenburg–West Pomerania, Saxony, Saxony-Anhalt, Thuringia.
¶Northern states: Schleswig-Holstein, Hamburg, Lower Saxony, Bremen, Berlin, Brandenburg, Mecklenburg-West Pomerania.
#Middle states: Nordrhine-Westfalia, Hesse, Saxony, Saxony-Anhalt, Thuringia.
**Southern states: Rhineland-Palatinate, Baden-Württemberg, Bavaria, Saarland.
††Defined as persons holding a foreign citizenship.