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Volume 21, Number 11—November 2015
Dispatch

Pneumococcal Infection among Children before Introduction of 13-Valent Pneumococcal Conjugate Vaccine, Cambodia

Paul TurnerComments to Author , Claudia Turner, Kuong Suy, Sona Soeng, Sokeng Ly, Thyl Miliya, David Goldblatt, and Nicholas P.J. Day
Author affiliations: Cambodia Oxford Medical Research Unit, Siem Reap, Cambodia (P. Turner, C. Turner, K. Suy); Mahidol University, Bangkok, Thailand (P. Turner, C. Turner, N.P.J. Day); University of Oxford, Oxford, UK (P. Turner. C. Turner, N.P.J. Day); Angkor Hospital for Children, Siem Reap (S. Soeng, S. Ly, T. Miliya); University College London, London, UK (D. Goldblatt)

Main Article

Table 1

Characteristics of 974 children enrolled in outpatient pneumococcal colonization surveys at Angkor Hospital for Children, Siem Reap, Cambodia, January and August 2014*

Characteristic Overall January 2014 August 2014 p value†
Total no. enrolled 974 455 519
Age, median (IQR)
2.5 (0.9–5.1)
1.9 (0.9–4.1)
2.9 (1.1–6.0)
<0.001
Age category, no. (%)
1–11 mo 262 (26.9) 142 (31.2) 120 (23.1) 0.005
12–59 mo 459 (47.1) 231 (50.8) 228 (43.9) 0.03
5–15 y
253 (26.0)
82 (18.0)
171 (33.0)
<0.001
Male sex, no. (%)
499 (51.2)
241 (53.0)
258 (49.7)
0.3
Reason for outpatient visit, no. (%)
Upper respiratory tract infection 794 (81.5) 394 (86.6) 400 (77.1) <0.001
Gastroenteritis 92 (9.5) 47 (10.3) 45 (8.7) 0.4
Other
88 (9.0)
14 (3.1)
74 (14.2)
<0.001
Antimicrobial drug use in preceding month, no. (%)‡
453/967 (46.8)
149/453 (32.9)
175/514 (34.0)
0.7
Household size, median (IQR) 5 (4–6) 5 (4–7) 5 (4–6) 0.01
Other children <5 y of age in household, no. (%) 841/973 (86.4) 422/454 (93.0) 419 (80.7) <0.001
Attendance at school or daycare, no. (%) 293/973 (30.1) 105/454 (23.1) 188 (36.2) <0.001

*Weather conditions were cool and dry in January and hot and wet in August. Where data were missing, an alternate denominator is included in the affected cell. IQR, interquartile range.
†For proportions, comparisons were made by using the χ2 test. For continuous variables, comparisons were made by using the Wilcoxon rank-sum test.
‡Includes definite and possible (unknown systemic medication) consumption in the community before outpatient visit.

Main Article

Page created: November 18, 2015
Page updated: November 18, 2015
Page reviewed: November 18, 2015
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