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Volume 21, Number 12—December 2015
Dispatch

Factors Associated with Severe Leptospirosis, Martinique, 2010–2013

Patrick HochedezComments to Author , Rafaelle Theodose, Claude Olive, Pascale Bourhy, Guillaume Hurtrel, Nicolas Vignier, Hossein Mehdaoui, Ruddy Valentino, Roland Martinez, Jean-Marie Delord, Cécile Herrmann, Isabelle Lamaury, Raymond Césaire, Mathieu Picardeau, and André Cabié
Author affiliations: Centre Hospitalier Universitaire de Martinique, Fort de France, Martinique, France (P. Hochedez, R. Theodose, C. Olive, G. Hurtrel, N. Vignier, H. Mehdaoui, R. Valentino, R. Césaire, A. Cabié); Université des Antilles et de la Guyane, Fort de France, Martinique, and Pointe à Pitre, Guadeloupe, France (P. Hochedez, R. Theodose, C Olive, C. Herrmann, I. Lamaury, R. Césaire); Institut Pasteur, Paris, France (P. Bourhy, M. Picardeau); Centre Hospitalier Universitaire Avicenne, Bobigny, France (N. Vignier); Centre Hospitalier de Trinité, Trinité, Martinique (R. Martinez); Centre Hospitalier du Lamentin, Lamentin, Martinique (J.-M. Delord); Centre Hospitalier Universitaire de Pointe à Pitre, Guadeloupe (C. Herrmann, I. Lamaury); Institut National de la Santé et de la Recherche Medicale, Paris (A. Cabié)

Main Article

Table 1

Clinical characteristics of 102 patients with quantitative PCR–confirmed leptospirosis, by disease severity, Martinique, 2010–2013

Characteristic All patients, n = 102, no. (%) Patients with severe disease, n = 12, no. (%) Patients with nonsevere disease, n = 90, no. (%) p value
Fever >38°C 88 (86.3) 9 (75) 79 (87.8) 0.364
Hypotension* 10 (9.8) 5 (41.7) 5 (5.6) 0.002
Cough 12 (11.8) 3 (25) 9 (10) 0.148
Abnormalities at chest auscultation 7 (6.9) 4 (33.3) 3 (3.3) 0.003
Abdominal pain 30 (29.4) 5 (41.7) 25 (27.8) 0.329
Vomiting 42 (41.2) 5 (41.7) 37 (41.1) 1
Diarrhea 30 (29.4) 3 (25) 27 (30) 1
Icterus 39 (38.2) 9 (75) 30 (33.3) 0.009
Conjunctival suffusion 20 (19.6) 1 (8.3) 19 (21.1) 0.45
Consciousness disorders 2 (1.6) 1 (8.3) 1 (1.1) 0.2
Hemorrhage† 6 (5.9) 1 (8.3) 5 (5.6) 0.54
Oliguria** or anuria‡ 8 (7.8) 5 (41.7) 3 (3.3) 0.0001

*Systolic blood pressure <90 mm Hg.
†Hemoptysis, hematuria, bleeding of the gums, or hematemesis.
‡<500 mL urine/day.

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Page created: November 17, 2015
Page updated: November 17, 2015
Page reviewed: November 17, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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